PMID: 332188Jan 1, 1977Paper

Controlled double-blind trial on the clinical effects of the chenodeoxycholic acid-fentonium bromide combination in the symptomatic treatment of biliary spastic-dyskinetic conditions

Arzneimittel-Forschung
S Ricciardi, R Cerqua

Abstract

A double-blind controlled trial was carried out to compare the effects of chenodeoxycholic acid combined with fentonium bromide (respectively, 125 and 20 mg for each capsule) vs. biliary acid alone in the treatment of biliary dyskinetic conditions with or without gallstones. Observations, concerning altogether 30 patients, showed a significantly higher and quicker efficacy of the combination (3--4 capsules daily during 14 days), in comparison to chenodeoxycholic acid alone, on the group of "painful" symptoms; on the contrary, no significant difference was noticed with regard to efficacy on "dyspeptic" symptoms. These results show the significant contribution of fentonium bromide and give experimental evidence of the usefulness and therapeutical advantages of the preparation under study.

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.