PMID: 236810May 17, 1975Paper

Controlled study of atenolol in treatment of hypertension

British Medical Journal
L HanssonA Westerlund

Abstract

The antihypertensive effect of atenolol, a new beta-1-receptor blocking agent, was studied in a double-blind trial in which 45 patients with essential hypertension were randomly assigned to placebo or atenolol treatment. Atenolol caused a statistically significant and clinically relevant reduction of blood pressure. The optimum daily dose for moderately severe hypertension was considered to be 200 mg. Several irrelevant side effects were collected by the use of a check list, but there was no difference in the number of complaints during placebo and active treatment. Atenolol has a useful antihypertensive effect and, at least theoretically, has advantages over other beta-adrenergic blocking agents.

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Jan 31, 1979·Psychopharmacology·A A LandauerF W Prott
Jan 1, 1985·European Journal of Clinical Pharmacology·A Westerlund
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Hypertensive Disease
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