PMID: 44015Oct 18, 1979

Controlled therapeutic study of spontaneous bucco-linguo-facial dyskinesias (author's transl)

La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
P J Delwaide, M Desseilles

Abstract

A triple blind study has been conducted according to an original methodology to compare the effects of thioproperazine and tiapride on the spontaneous bucco-linguo-facial dyskinesias in the elderly. Side effects have been balanced to obtain a quantitative evaluation. Thioproperazine (3 x 3 mg/day) and tiapride (3 x 100 mg/day) reduce both significantly the number of dyskinesias, the former being more active than the latter. On the other hand, side effects of thioproprerazine are significantly higher than those of tiapride which are themselves not different from those induced by the placebo. Taking into account these results and the fact that dyskinesias represent a benign condition, the tiapride appears to be the first choice drug.

Related Concepts

Tiapamil
Genus Bucco
Face
Cheek Structure
Dyskinetic Syndrome
Etat Marbre
Clinical Trials
Thioproperazine
Tongue
Benzamides

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