PMID: 15244286Jul 13, 2004Paper

Controlled ultrasound tissue erosion

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Zhen XuCharles A Cain

Abstract

The ability of ultrasound to produce highly controlled tissue erosion was investigated. This study is motivated by the need to develop a noninvasive procedure to perforate the neonatal atrial septum as the first step in treatment of hypoplastic left heart syndrome. A total of 232 holes were generated in 40 pieces of excised porcine atrial wall by a 788 kHz single-element transducer. The effects of various parameters [e.g., pulse repetition frequency (PRF), pulse duration (PD), and gas content of liquid] on the erosion rate and energy efficiency were explored. An Isppa of 9000 W/cm2, PDs of 3, 6, 12, and 24 cycles; PRFs between 1.34 kHz and 66.7 kHz; and gas saturation of 40-55% and 79-85% were used. The results show that very short pulses delivered at certain PRFs could maximize the erosion rate and energy efficiency. We show that well-defined perforations can be precisely located in the atrial wall through the controlled ultrasound tissue erosion (CUTE) process. A preliminary in vivo experiment was conducted on a canine subject, and the atrial septum was perforated using CUTE.

References

Jan 1, 1990·Ultrasound in Medicine & Biology·S Z ChildE L Carstensen
Nov 1, 1990·The Journal of the Acoustical Society of America·C K Holland, R E Apfel
Sep 1, 1988·Ultrasonics·A A AtchleyR A Roy
Jun 1, 1988·The Journal of the Acoustical Society of America·J B Fowlkes, L A Crum
Aug 1, 1984·The Journal of the Acoustical Society of America·H G Flynn, C C Church
Jan 1, 1981·Ultrasound in Medicine & Biology·V CiaravinoM W Miller
Jan 1, 1994·Ultrasound in Medicine & Biology·L A FrizzellC Lee
Jan 1, 1995·Ultrasound in Medicine & Biology·D DaleckiE L Carstensen
Nov 11, 1998·Ultrasound in Medicine & Biology·N B Smith, K Hynynen
Sep 25, 1999·Physics in Medicine and Biology·P HuberM Wannenmacher
May 23, 2001·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·P P ChangL A Crum
Jan 24, 2003·Annals of Biomedical Engineering·Tarek H El-BialyLeon A Frizzell
Feb 6, 2003·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Kouji NaruseYuko Mikuni-Takagaki
Mar 6, 2003·Sports Medicine·Stuart J Warden
Feb 2, 2008·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·H WanC Cain

❮ Previous
Next ❯

Citations

Jun 20, 2008·Physics in Medicine and Biology·D E KruseK W Ferrara
Aug 4, 2010·Journal of Endourology·Timothy L HallWilliam W Roberts
Nov 26, 2010·Journal of Endourology·Alexander P DuryeaWilliam W Roberts
Feb 12, 2005·The Journal of the Acoustical Society of America·Zhen XuCharles A Cain
May 3, 2007·The Journal of the Acoustical Society of America·Zhen XuCharles A Cain
Jul 7, 2007·The Journal of the Acoustical Society of America·Zhen XuCharles A Cain
Aug 7, 2008·The Journal of the Acoustical Society of America·Timothy A Bigelow
Oct 7, 2011·The Journal of the Acoustical Society of America·Adam D MaxwellZhen Xu
Mar 26, 2011·Radiology·Clare M C TempanyFerenc A Jolesz
Oct 1, 2013·Journal of Neurosurgery·Ryan AlkinsKullervo Hynynen
Jan 28, 2009·Ultrasound in Medicine & Biology·Timothy A BigelowFrances C Sailer
May 2, 2015·Ultrasound in Medicine & Biology·Kuang-Wei LinCharles A Cain
Jan 28, 2015·Ultrasound in Medicine & Biology·Xi ZhangZhen Xu
Jun 20, 2016·Ultrasound in Medicine & Biology·Yubo GuanMingxi Wan
Aug 16, 2016·European Heart Journal Cardiovascular Imaging·Olivier VillemainEmmanuel Messas
Dec 14, 2005·Ultrasound in Medicine & Biology·Zhen XuCharles A Cain
Apr 25, 2016·Ultrasound in Medicine & Biology·Kenneth B BaderChristy K Holland
Nov 2, 2013·BJU International·George R SchadeWilliam W Roberts
Jul 25, 2015·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Viksit KumarDonald S Sakaguchi
Jan 10, 2006·The Journal of Thoracic and Cardiovascular Surgery·Emile A BachaZiyad M Hijazi
Jan 16, 2020·Journal for Immunotherapy of Cancer·Shibin QuClifford Suhyun Cho
Jun 21, 2007·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·C C CoussiosR A Roy
Sep 16, 2010·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M FujisakiS Takamoto
Sep 11, 2013·Physics in Medicine and Biology·Chia-Lun YehPo-Ling Kuo
May 23, 2014·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Nir LipsmanAndres M Lozano
Feb 27, 2015·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·David E Goertz
May 31, 2019·Physics in Medicine and Biology·Samuel A HendleyKenneth B Bader
Mar 12, 2020·Stem Cells Translational Medicine·Daniel D LiuAvnesh S Thakor
Jan 8, 2008·The Journal of the Acoustical Society of America·Aaldert Zijlstra, Claus Dieter Ohl
Jun 26, 2010·Journal of Endourology·Nicholas R StynWilliam W Roberts
Aug 17, 2012·Journal of Magnetic Resonance Imaging : JMRI·Kullervo Hynynen
Sep 21, 2010·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Gabe E OwensZhen Xu
Nov 1, 2013·Journal of Endourology·Adam D MaxwellThomas S Lendvay
Aug 12, 2014·Physics in Medicine and Biology·Adam D MaxwellZhen Xu
Nov 8, 2014·Current Eye Research·Suresh Kanna Murugappan, Yufeng Zhou
Sep 21, 2013·Experimental Biology and Medicine·Zeynep ItahDevrim Gozuacik
May 23, 2015·The Journal of the Acoustical Society of America·Hong HuMingxi Wan
Dec 21, 2016·Physics in Medicine and Biology·Eli VlaisavljevichZhen Xu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Zhen XuCharles A Cain
Annual Review of Biomedical Engineering
Diane Dalecki
© 2022 Meta ULC. All rights reserved