PMID: 8594127Dec 1, 1995Paper

Controlling for socioeconomic confounding using regression methods

Journal of Epidemiology and Community Health
J F BithellT J Vincent

Abstract

To describe the advantages of using Poisson regression methods as an alternative to standardisation when computing expected numbers of disease occurrences adjusted for possible confounding factors. The problem of assessing the adequacy of model fit when the expectations are small is addressed by analytical calculations and by simulation. The method is illustrated with data from the national register of childhood tumours. The tumour data are recorded in a national register. England, Scotland, and Wales. The cases considered are all children registered with leukaemia or non-Hodgkin lymphoma under the age of 15 years between 1966-87. The methods show a significant variation of leukaemia incidence in relation to the Register General's standard region and a negative association with socioeconomic deprivation, as measured by the Townsend index. After allowing for these variables, the incidence seems to be reasonably homogeneous throughout the population, in the sense that the residual deviance does not seem to be much larger than would be expected by chance. The methods described have major advantages over standardisation in controlling for confounding, both in terms of flexibility of factor selection and assessment and also in the a...Continue Reading

References

Mar 1, 1995·Environment & Planning a·S Openshaw, L Rao

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Citations

May 7, 2002·International Journal of Cancer. Journal International Du Cancer·Heather O Dickinson, Louise Parker
Aug 17, 1999·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·F E AlexanderN Wray
Dec 1, 1996·Journal of Epidemiology and Community Health·A Lawson
Oct 9, 1998·Journal of Epidemiology and Community Health·M R Law, J K Morris
Jul 29, 2003·Occupational and Environmental Medicine·J AlguacilP Gustavsson
Jun 8, 1999·American Journal of Public Health·M Pollán, P Gustavsson
Oct 12, 2002·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R C ParslowP A McKinney
Feb 11, 2011·Birth Defects Research. Part A, Clinical and Molecular Teratology·Lili XuJun Zhu
Aug 29, 2000·Statistics in Medicine·C PascuttoP Elliott
Jan 31, 2004·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·H O DickinsonL Parker
Dec 31, 1998·Electrophoresis·S J KokU A Brinkman
Sep 16, 1999·British Journal of Cancer·H O Dickinson, L Parker
Feb 5, 2005·Statistical Methods in Medical Research·Alan R Dabney, Jon C Wakefield

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