Controlling particle size in the Stöber process and incorporation of calcium

Journal of Colloid and Interface Science
Sarah L GreasleyJulian R Jones

Abstract

The Stӧber process is commonly used for synthesising spherical silica particles. This article reports the first comprehensive study of how the process variables can be used to obtain monodispersed particles of specific size. The modal particle size could be selected within in the range 20-500 nm. There is great therapeutic potential for bioactive glass nanoparticles, as they can be internalised within cells and perform sustained delivery of active ions. Biodegradable bioactive glass nanoparticles are also used in nanocomposites. Modification of the Stӧber process so that the particles can contain cations such as calcium, whilst maintaining monodispersity, is desirable. Here, whilst calcium incorporation is achieved, with a homogenous distribution, careful characterisation shows that much of the calcium is not incorporated. A maximum of 10 mol% CaO can be achieved and previous reports are likely to have overestimated the amount of calcium incorporated.

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Citations

Nov 9, 2019·Nanomaterials·Francesca OltolinaAntonia Follenzi
Dec 28, 2016·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Kai ZhengAldo R Boccaccini
Mar 1, 2019·Journal of Functional Biomaterials·Alejandra Ruiz-ClavijoNichola J Coleman
Jan 1, 2018·Journal of Sol-gel Science and Technology·Marion A BourebrabAlan Taylor
Sep 12, 2020·Advances in Colloid and Interface Science·Masami Kawaguchi
Mar 7, 2021·Polymers·Dafna Heiman-BursteinSamuel Kenig
Feb 2, 2018·ACS Applied Materials & Interfaces·Chang-Min YoonJyongsik Jang
Apr 12, 2019·Journal of Colloid and Interface Science·Breno R BarrioniMarivalda de M Pereira
Jun 18, 2020·ACS Omega·Natalia Pajares-Chamorro, Xanthippi Chatzistavrou
Oct 9, 2021·Nanoscale·Bárbara CasteleiroJosé Paulo Sequeira Farinha
Nov 1, 2020·Journal of Colloid and Interface Science·Pramila P Ghimire, Mietek Jaroniec

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