Controlling the porosity and microarchitecture of hydrogels for tissue engineering.

Tissue Engineering. Part B, Reviews
Nasim AnnabiFariba Dehghani

Abstract

Tissue engineering holds great promise for regeneration and repair of diseased tissues, making the development of tissue engineering scaffolds a topic of great interest in biomedical research. Because of their biocompatibility and similarities to native extracellular matrix, hydrogels have emerged as leading candidates for engineered tissue scaffolds. However, precise control of hydrogel properties, such as porosity, remains a challenge. Traditional techniques for creating bulk porosity in polymers have demonstrated success in hydrogels for tissue engineering; however, often the conditions are incompatible with direct cell encapsulation. Emerging technologies have demonstrated the ability to control porosity and the microarchitectural features in hydrogels, creating engineered tissues with structure and function similar to native tissues. In this review, we explore the various technologies for controlling the porosity and microarchitecture within hydrogels, and demonstrate successful applications of combining these techniques.

References

Feb 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·I V YannasG F Murphy
Dec 1, 1994·Journal of Pharmaceutical Sciences·S D YeoT M Przybycien
Jun 1, 1996·Journal of Pharmaceutical Sciences·M A WintersS J Prestrelski
Mar 12, 1999·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·G Vunjak-NovakovicL E Freed
Jul 14, 1999·Biomaterials·H W KangY Ikada
Jan 21, 2000·Journal of Controlled Release : Official Journal of the Controlled Release Society·M H SheridanD J Mooney
May 29, 2000·Journal of Biomedical Materials Research·G ChenT Tateishi
Mar 13, 2002·Biomacromolecules·Jamil A MatthewsGary L Bowlin
Apr 12, 2002·Journal of Biomedical Materials Research·Wan-Ju LiFrank K Ko
Sep 26, 2002·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Soo Won SuhIn-Wook Choo
Jul 31, 2003·Journal of Biomedical Materials Research. Part a·Tithi Dutta RoyJ Russell Parsons
Oct 2, 2003·Nature Biotechnology·Shuguang Zhang
Nov 19, 2003·Journal of Biomedical Materials Research. Part a·Wan-Ju LiRocky S Tuan
Jul 2, 2004·Analytical Chemistry·Ali KhademhosseiniRobert Langer
Mar 2, 2005·Tissue Engineering·Christina FidkowskiYadong Wang
Jul 9, 2005·Nature Materials·Scott J Hollister
Dec 20, 2005·Journal of Materials Science. Materials in Medicine·L DraghiM C Tanzi
Jan 3, 2006·Colloids and Surfaces. B, Biointerfaces·Wen-Ching LinMing-Chien Yang
Feb 14, 2006·Proceedings of the National Academy of Sciences of the United States of America·Millicent C FordErin B Lavik
Feb 16, 2006·Proceedings of the National Academy of Sciences of the United States of America·Ali KhademhosseiniJoseph P Vacanti
Apr 8, 2006·Microvascular Research·Kenneth M ChrobakJoe Tien
May 17, 2006·Acta Biomaterialia·Dominique J GriffonAnn L Johnson
Jun 15, 2006·Tissue Engineering·Quynh P PhamAntonios G Mikos
Jun 22, 2006·Journal of Biomedical Materials Research. Part a·Ali KhademhosseiniJason A Burdick
Jul 11, 2006·Biomaterials·Judy YehAli Khademhosseini
Aug 10, 2006·Annals of Biomedical Engineering·Karina ArcauteRyan B Wicker
Nov 17, 2006·Journal of Biomedical Materials Research. Part a·Xuemei WuCharles W Patrick
Dec 21, 2006·Journal of Biomaterials Science. Polymer Edition·Ali KhademhosseiniRobert Langer
Jan 2, 2007·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Valerie Liu TsangSangeeta N Bhatia
Apr 3, 2007·Biomaterials·Stephanie J BryantBuddy D Ratner
Apr 28, 2007·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·John J A BarrySteven M Howdle

❮ Previous
Next ❯

Citations

Sep 6, 2011·Journal of Cardiovascular Translational Research·Lei Tian, Steven C George
Mar 1, 2012·Archives of Pharmacal Research·Ji Won ShinJung-Woog Shin
Dec 10, 2013·Biomaterials·Marine VerhulselJean-Louis Viovy
Dec 24, 2013·International Journal of Biological Macromolecules·Celine D G Abueva, Byong-Taek Lee
Jun 22, 2013·ACS Applied Materials & Interfaces·Eunice Sok Ping LeongJinghua Teng
Jul 21, 2012·ACS Chemical Neuroscience·Giuseppe PeralePietro Veglianese
Sep 12, 2012·Tissue Engineering. Part a·Vahid HosseiniAli Khademhosseini
Aug 6, 2011·Tissue Engineering. Part B, Reviews·Jelena Rnjak-Kovacina, Anthony S Weiss
Feb 25, 2011·Stem Cell Research & Therapy·Penny M Gilbert, Helen M Blau
Mar 29, 2014·American Journal of Veterinary Research·Jamie A TextorFern Tablin
Oct 23, 2013·Applied Biochemistry and Biotechnology·Victor M BalcãoMarta M D C Vila
Jan 15, 2014·Tissue Engineering. Part a·Stephanie A FisherMolly S Shoichet
Jun 15, 2010·Biomaterials·Zuratul A A HamidGreg G Qiao
Jun 7, 2014·Annual Review of Biomedical Engineering·Piyush BajajRashid Bashir
Dec 7, 2010·Acta Biomaterialia·Chengdong JiFariba Dehghani
Feb 18, 2016·Journal of Materials Science. Materials in Medicine·Jianming RuanKechao Zhou
Dec 23, 2015·Acta Biomaterialia·Ali NavaeiMehdi Nikkhah
Jun 5, 2014·Biotechnology and Bioengineering·Chen-Chie WangIng-Ho Chen
Feb 3, 2016·Tissue Engineering. Part C, Methods·Hye Rin KwagDavid H Gracias
Dec 10, 2015·Advanced Healthcare Materials·Nermin Seda Kehr, Kristina Riehemann
Jul 19, 2011·Trends in Biotechnology·Christina L RandallDavid H Gracias
May 7, 2011·Current Opinion in Biotechnology·Fariba Dehghani, Nasim Annabi
Dec 26, 2015·Ultrasonics Sonochemistry·M Soledad BelluzoM Susana Cortizo
Mar 2, 2016·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Justinas MačiulaitisRomaldas Mačiulaitis
Jul 16, 2013·Journal of Biomedical Materials Research. Part a·Sunita Nayak, S C Kundu
Feb 13, 2013·Journal of Tissue Engineering and Regenerative Medicine·Sárka KubinováEva Syková
Dec 15, 2012·Journal of Tissue Engineering and Regenerative Medicine·Işıl Gerçek BeşkardeşMenemşe Gümüşderelioğlu
Jun 12, 2014·Journal of Tissue Engineering and Regenerative Medicine·Jin Woo BaeKi Dong Park
Oct 17, 2015·Biomacromolecules·Tomáš SedlačíkFrantišek Rypáček
Nov 5, 2011·Journal of Tissue Engineering and Regenerative Medicine·J BrahmR Schmidt
Sep 14, 2011·Biotechnology Progress·Hai-Hua SunFa-Ming Chen

❮ Previous
Next ❯

Methods Mentioned

BETA
confocal microscopy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.