Abstract
Conduction across the atrioventricular junctions had long been controversial, with arguments raging as to whether such conduction was myogenic or neurogenic. The landmark study of Tawara in 1906 established the existence of an axis of histologically specialized myocardial cells contained within fibrous sheaths as being responsible for rapid conduction from the atrial to the ventricular myocardium. Keith and Flack then demonstrated that the atrial impulse was generated in the sinus node, with subsequent slowing within the atrioventricular node of Tawara. The detailed reviews of Aschoff and Monckeberg then emphasized the morphological features that permit unequivocal recognition of the nodes, along with rapidly conducting tracts. It is now pertinent that we remember these original criteria for anatomical recognition as we discuss the steps involved in the development of these conducting structures from their embryologic primordiums. In this review, we restate the criteria of Aschoff and Monckeberg, then discuss their relevance to the developmental issues, emphasizing that all myocardial cells have the potential to conduct. The important issues, therefore, are the changes that occur as the heart itself changes from a solitary musc...Continue Reading
References
Oct 1, 1975·Circulation Research·M O Masuda, A Paes de Carvalho
Oct 1, 1992·Circulation·W H LamersR H Anderson
Jan 1, 1992·The Anatomical Record·A WesselsA F Moorman
Jan 1, 1990·Anatomy and Embryology·T IkedaT Matsuo
Mar 21, 1973·Zeitschrift für Zellforschung und mikroskopische Anatomie·J Tranum-Jensen, F Bojsen-Moller
Dec 1, 1972·British Heart Journal·R H Anderson, I M Taylor
Oct 1, 1972·The American Journal of Cardiology·R IsaacsonD C McGoon
Mar 1, 1968·The Anatomical Record·G H PaffT C Harrell
Jan 1, 1983·The American Journal of Physiology·C C LiewM J Sole
May 1, 1993·Anatomy and Embryology·M NakagawaT K Borg
Aug 22, 2001·Heart·S Y HoD Sánchez-Quintana
May 23, 2002·Genes & Development·Petra E M H HabetsVincent M Christoffels
May 14, 2003·Journal of Cardiovascular Electrophysiology·Richard P KondoSylvia M Evans
Aug 2, 2003·Journal of Cardiovascular Electrophysiology·Alejandro Perez-LugonesAndrea Natale
Oct 1, 1963·American Heart Journal·T N JAMES
Sep 25, 2003·Physiological Reviews·Antoon F M Moorman, Vincent M Christoffels
Mar 17, 2004·Cardiovascular Research·Donald B HooverRodney L Parsons
Mar 20, 2004·Journal of Cardiovascular Electrophysiology·Monique R M JongbloedAdriana C Gittenberger-De Groot
Citations
Dec 10, 2014·Zhurnal evoliutsionnoĭ biokhimii i fiziologii·S L SmirnovaM P Roshchevskii
Jul 8, 2008·The Journal of Thoracic and Cardiovascular Surgery·Robert H AndersonPaul P Lunkenheimer
Nov 16, 2005·The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology·Florence Rothenberg, Igor R Efimov
Nov 8, 2012·Journal of Cardiovascular Electrophysiology·Robert H Anderson, Antoon F M Moorman
Jun 16, 2015·Medical Image Analysis·Rubén CárdenesOscar Camara
Dec 3, 2014·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Eduardo Back SternickHein J J Wellens
Nov 21, 2014·PloS One·Lubov B MitrofanovaEvgeny N Mikhaylov
May 18, 2012·Reproductive Sciences·Monique W M de LaatCarrie Ris-Stalpers
Apr 30, 2005·Circulation Research·Glenn I Fishman
May 14, 2011·Cardiovascular Research·Alex V PostmaConnie R Bezzina
Apr 19, 2016·Journal of Cardiovascular Development and Disease·Robert H AndersonShumpei Mori
May 31, 2019·Pacing and Clinical Electrophysiology : PACE·Jacques Billette, Rafik Tadros
Sep 29, 2021·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Yolanda MacíasRobert H Anderson