Controversies in Anticoagulant Therapy in Vitreo-Retinal Surgery

Current Pharmaceutical Design
Andrzej GrzybowskiPaulina Kupidura

Abstract

The number of elderly patients using anticoagulant and antiplatelet treatment in prevention of thromboembolism has significantly increased in recent years. It was believed for many years that those patients may be at higher risk for hemorhages during ocular surgery. Different strategies were proposed to prevent these complications, including discontinuation of anticoagulants, dose reduction, or substitution with low molecular weight heparin. The objective of this work was to evaluate the results of studies presenting the results of vitreoretinal surgeries in patients continuing antiplatelet and/or anticoagulant treatment. We performed a PubMed search of possible intraoperative and postoperative hemorrhages in patients receiving anticoagulant and/or antiplatelet therapy during vitreoretinal surgery in 2007-2014. In most of the studies reviewed there was no substantial increase in intraoperative and postoperative hemorrhages risks during vitreoretinal surgery. However, in some studies, a substantially increased risk has been identified. We conclude that the available data is insufficient to decide whether to continue or discontinue anticoagulant and/or antiplatelet therapy during vitreoretinal surgery and we recommend an individu...Continue Reading

Citations

Jan 18, 2018·Acta Ophthalmologica·Sirpa LoukovaaraJari Haukka
Apr 1, 2018·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Cyril MeillonCatherine Creuzot-Garcher
Apr 1, 2018·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Andrzej Grzybowski, Piotr Kanclerz
Aug 4, 2021·Archivos De La Sociedad Española De Oftalmología·J C Herranz-HerasS Pérez-Trigo
Dec 30, 2020·Archivos de la Sociedad Española de Oftalmología·J C Herranz-HerasS Pérez-Trigo

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