Conundrums and Caveats in Neuroendocrine Tumors of the Pancreas

Surgical Pathology Clinics
Laura H Tang, David S Klimstra

Abstract

Pancreatic neuroendocrine tumors (Pan-NETs) are the second most common epithelial neoplasm of the pancreas after ductal adenocarcinoma. They can be clinically defined as functional, nonfunctional, and hereditary. This review addresses typical and atypical pathologic features of Pan-NETs, with a focus on practical issues involved in differential diagnosis, immunohistochemical work-up, intraoperative frozen section interpretation, sources of diagnostic errors, and classification. The diagnosis of a Pan-NET requires analysis of all available clinical and radiographic information and pathologic characteristics of the tumor, and it is crucial to understand the clinical impact of the pathologic interpretation.

References

Nov 1, 1990·Annals of Surgery·J A NortonR T Jensen
May 9, 2001·The American Journal of Surgical Pathology·M P HoangJ Albores-Saavedra
Sep 11, 2001·Genes, Chromosomes & Cancer·P S MooreA Scarpa
Jun 1, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Steven N HochwaldDavid S Klimstra
Dec 14, 2004·Cancer Genetics and Cytogenetics·Giovanna FloridiaDomenica Taruscio
Apr 16, 2005·The American Journal of Surgical Pathology·Hind NassarDavid S Klimstra
Aug 13, 2005·The American Journal of Surgical Pathology·Sui Y ZeeDavid S Klimstra
Sep 13, 2006·Virchows Archiv : an International Journal of Pathology·G RindiUNKNOWN European Neuroendocrine Tumor Society (ENETS)
May 9, 2007·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·David S Klimstra
Dec 11, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Cristina R FerronePeter J Allen
Mar 25, 2008·The American Journal of Surgical Pathology·Jinru ShiaDavid S Klimstra
Dec 3, 2008·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Sara EkebladBarbro Eriksson
Mar 6, 2009·Archives of Pathology & Laboratory Medicine·Paola CapelliAldo Scarpa
Mar 6, 2009·Archives of Pathology & Laboratory Medicine·David S KlimstraRalph H Hruban
Aug 29, 2009·Neuroendocrinology·Dik J KwekkeboomUNKNOWN European Neuroendocrine Tumor Society
Feb 4, 2010·Archives of Pathology & Laboratory Medicine·Mary Kay WashingtonUNKNOWN Members of the Cancer Committee, College of American Pathologists
Feb 4, 2010·Archives of Pathology & Laboratory Medicine·Mary Kay WashingtonUNKNOWN Members of the Cancer Committee, College of American Pathologists
Feb 4, 2010·Archives of Pathology & Laboratory Medicine·Mary Kay WashingtonUNKNOWN Members of the Cancer Committee, College of American Pathologists
Feb 25, 2010·Annals of Surgical Oncology·Stephen B Edge, Carolyn C Compton
Mar 23, 2010·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Aldo ScarpaMassimo Falconi
Jul 29, 2010·Pancreas·Matthew H KulkeUNKNOWN North American Neuroendocrine Tumor Society (NANETS)
Oct 1, 2010·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·R J Hicks
Dec 21, 2010·Seminars in Oncology·Jorge A Carrasquillo, Clara C Chen

❮ Previous
Next ❯

Citations

Nov 28, 2014·Abdominal Imaging·Tae Won ChoiByung Ihn Choi
Apr 17, 2020·Archives of Pathology & Laboratory Medicine·Laura H Tang
Jul 5, 2012·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Laura H TangChris R Harris

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adenoma, Islet Cell

Islet Cell Adenoma arises in the islet cells, which are insulin producing cells of the pancreas. These tumors can be either malignant or benign. Discover the latest research on Islet Cell Adenoma here.

Carcinoma, Islet Cell (Keystone)

Islet Cell Carcinoma or Pancreatic Neuroendocrine Tumours arise in the hormone producing cells of the pancreas. These tumors can be either malignant or benign. Discover the latest research on islet cell carcinoma in this feed.

Carcinoma, Islet Cell

Islet Cell Carcinoma or Pancreatic Neuroendocrine Tumours arises in the hormone producing cells of the pancreas. These tumors can be either malignant or benign. Discover the latest research on Islet Cell Carcinoma here.

Related Papers

Expert Review of Gastroenterology & Hepatology
Antonio PeaLaura D Wood
Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
Roberta BombardieriPaolo Curatolo
© 2021 Meta ULC. All rights reserved