Conventional semen parameters and DNA fragmentation in relation to fertility status in a Greek population

European Journal of Obstetrics, Gynecology, and Reproductive Biology
E EvgeniB Asimakopoulos

Abstract

Our study aimed to investigate the possible correlations between conventional seminal parameters and DNA fragmentation in specific groups of Greek men, selected in relation to their fertility history and to verify the validity of the recent WHO reference values for the basic semen analysis in this population. A total of 770 subject data were evaluated in three distinct groups: fertile men with children naturally conceived within one year of unprotected intercourse (n=78), subfertile men, having achieved pregnancies either naturally or by Assisted Reproduction Techniques, not resulting in live births (n=153) and infertile men, failing to produce either pregnancies or children (n=539). Semen volume, sperm concentration, total count, rapid and total progressive motility and morphology were evaluated following the World Health Organization (2010) methods. DNA fragmentation was assessed by the Sperm Chromatin Dispersion assay. The 5th percentile, as well as the 95% confidence intervals (CI) for each parameter, were calculated by the method of bootstrapping. Statistical correlations between the examined parameters were sought using the Spearman R test (p<0.05). A significant inverse correlation was established between DNA fragmentati...Continue Reading

References

Jul 26, 2002·Fertility and Sterility·Ramadan A SalehRakesh K Sharma
Dec 17, 2003·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·E Scott SillsM J Tucker
Aug 11, 2004·Fertility and Sterility·Elisabeth CarlsenNiels E Skakkebaek
May 5, 2005·Current Opinion in Obstetrics & Gynecology·Marcello SpanoDenny Sakkas
Oct 11, 2005·Fertility and Sterility·José Luis FernándezChristopher De Jonge
Feb 28, 2006·Fertility and Sterility·Kiran P NallellaAshok Agarwal
Jul 21, 2007·Reproduction : the Official Journal of the Society for the Study of Fertility·Sheena E M Lewis
Apr 29, 2008·Fertility and Sterility·Paul Cohen-BacrieMoncef Benkhalifa
Jun 24, 2008·Systems Biology in Reproductive Medicine·Sheena E M LewisJuan Alvarez
Nov 26, 2009·Human Reproduction Update·Trevor G CooperKirsten M Vogelsong
Jan 30, 2010·Asian Journal of Andrology·R John Aitken
Feb 23, 2010·Systems Biology in Reproductive Medicine·Jaime GosálvezRocio Nuñez
Aug 31, 2010·Reproductive Biomedicine Online·Tamer M SaidAshok Agarwal
Nov 9, 2010·Asian Journal of Andrology·Mona BungumAleksander Giwercman
Nov 26, 2010·Asian Journal of Andrology·Christopher L R BarrattSenga K Oxenham
Jul 21, 2011·Human Fertility : Journal of the British Fertility Society·Lars Björndahl
Mar 26, 2013·Molecular Medicine Reports·Huda Mossa OmranMariam Ghloom Dashti
May 23, 2013·Archivio italiano di urologia, andrologia : organo ufficiale [di] Società italiana di ecografia urologica e nefrologica·Giuseppina PelusoVincenzo Mirone
Jun 1, 2013·Journal of Assisted Reproduction and Genetics·Mausumi DasArmand Zini

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Citations

Feb 10, 2016·Archives of Toxicology·Franziska FerkSiegfried Knasmüller
May 2, 2018·Arab Journal of Urology·Chak-Lam Cho, Ashok Agarwal
Jun 15, 2019·International Journal of Environmental Research and Public Health·Kamil GillMałgorzata Piasecka
Apr 8, 2016·Current Opinion in Obstetrics & Gynecology·Ashok AgarwalSandro C Esteves
Jul 15, 2020·Andrologia·Marlon Martinez, Ahmad Majzoub
Sep 12, 2018·Clinical and Experimental Reproductive Medicine·Gi Young Kim
May 15, 2020·Journal of Assisted Reproduction and Genetics·Carlotta ZacàAndrea Borini
May 21, 2018·Reproductive Biology and Endocrinology : RB&E·Basmah Al OmraniHamad Al Sufyan
Mar 31, 2017·Reproduction : the Official Journal of the Society for the Study of Fertility·Arumugam KumaresanJane M Morrell
Aug 3, 2021·International Journal of Reproductive Medicine·Huda Mossa OmranVolker Ehemann

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