PMID: 8943119Nov 1, 1996Paper

Conventional treatment of biliary atresia: long-term results

Journal of Pediatric Surgery
J Valayer

Abstract

From 1968 to 1983, 271 patients were treated for biliary atresia by a group of surgeons from the same pediatric surgical unit, in Paris, using procedures adapted to the local anatomy and all derived from the Kasai technique. Eighty children have survived more than 10 years since the surgery, without the need for liver transplantation during the 10-year period. However, three children died subsequently from complications of the liver disease. Thirteen others later underwent liver transplantation, which accounted for three additional deaths. Thus, of the 64 patients left for study, 38 had a good result with respect to serum bilirubin level, but 18 of them still have symptoms of portal hypertension. Among another group of 14 patients with serum bilirubin levels between 18 and 36 mumol/L, 11 are leading a near-normal life. The mean follow-up period for this study is 14 years; the oldest patient is aged 24 years. One patient, already the mother of a normal son, is awaiting her second baby; she was treated by portocholecystostomy at 2 months of age. As a rule, liver transplantation should not be considered an alternative to the Kasai operation as initial treatment of biliary atresia. It may be the only form of treatment for survivors...Continue Reading

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Citations

Aug 26, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·C ChardotB Auvert
Aug 26, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J A Rudolph, W F Balistreri
Aug 8, 2007·Pediatric Surgery International·Tsubasa TakahashiAtsuyuki Yamataka
Dec 25, 2003·Journal of Pediatric Surgery·L W Ernest van HeurnPaul K H Tam
Sep 26, 2003·Journal of Pediatric Gastroenterology and Nutrition·Christophe Chardot
Sep 26, 2003·Journal of Pediatric Gastroenterology and Nutrition·Nedim HadzićGiorgina Mieli-Vergani
Feb 9, 2005·Journal of Pediatric Gastroenterology and Nutrition·Jessica L ArvayBarbara A Haber
Aug 21, 2012·Journal of Pediatric Gastroenterology and Nutrition·Benjamin L ShneiderUNKNOWN Childhood Liver Disease Research and Education Network
Feb 24, 2010·Journal of Indian Association of Pediatric Surgeons·V V S Chandrasekharam
Apr 16, 2003·Pediatric Radiology·Anne Poh Ann Tan KendrickCarolyn Eng Looi Tan
Aug 14, 2009·Expert Review of Gastroenterology & Hepatology·Jessi ErlichmanBarbara A Haber
Jan 5, 2016·The Journal of Pediatrics·Benjamin L ShneiderUNKNOWN Childhood Liver Disease Research Network (ChiLDReN)
Dec 27, 2005·Clinics in Liver Disease·Claus Petersen
Sep 18, 2004·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Brendan C VisserRyutaro Hirose
Dec 13, 1997·Journal of Pediatric Surgery·T HasegawaA Okada
Jun 24, 2004·Journal of Pediatric Surgery·Keiichi UchidaMasato Kusunoki
May 2, 2006·The Journal of Pediatrics·Christophe Chardot, Marie-Odile Serinet
Jul 13, 2014·The Journal of Pediatrics·Vicky Lee NgUNKNOWN Childhood Liver Disease Research and Education Network (CHiLDREN)
Nov 18, 2015·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·So Mi LeeSun Kyoung You
Jun 16, 2001·Indian Journal of Pediatrics·D K Gupta, S Dave
Jul 26, 2017·Journal of Pediatric Gastroenterology and Nutrition·Géraldine HerySophie Branchereau
Oct 3, 2006·Current Opinion in Anaesthesiology·S D Kelley, G A Gregory
Feb 14, 2019·Journal of Ultrasound·Marco Di SerafinoGianfranco Vallone
Dec 7, 2018·European Journal of Pediatrics·Satu Maria RuuskaMikko P Pakarinen

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