Convergence of nanotechnology and cardiovascular medicine : progress and emerging prospects

BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy
Nicole IversonPrabhas V Moghe

Abstract

Advances in the emergence of biological probes, materials, and analytical tools limited to the nanoscale size range, collectively referred to as 'nanotechnology', are increasingly being applied to the understanding and treatment of the major pathophysiological problems in cardiovascular medicine. Analytical techniques based on high-resolution microscopy and molecular-level fluorescence excitation processes capable of detecting nanoscale interactions have been used to elucidate cardiovascular pathology. Nanotechnology has also significantly impacted diagnostic intervention in cardiology, with the use of nanoparticles as contrast agents, for targeted biomedical imaging of vulnerable plaques, for detection of specific pathologic targets signaling the onset of atherosclerosis, and for tracking inflammatory events. Real-time nanoscale biosensors can be used to measure cardiovascular biomarkers, and nanopore sequencing has the potential to speed up the analysis of gene expression in cardiovascular disease. Potential therapeutic applications include the use of nanomaterials in cardiovascular devices, for delivery of drugs and bioactive molecules, or in novel technologies for reducing cholesterol accumulation and for dissolving clots.

References

Dec 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·F SangerA R Coulson
Jun 12, 1986·Nature·L M SmithL E Hood
Oct 16, 1980·The New England Journal of Medicine·U SuggR Lissner
Oct 24, 1996·The New England Journal of Medicine·J A Bittl
Nov 15, 1996·Circulation·I I JoffeM N Kotler
Aug 6, 2000·Circulation Research·K WalshH S Kim
Feb 13, 2001·Biochemical and Biophysical Research Communications·J D BarransC Liew
Apr 12, 2001·The New England Journal of Medicine·P W SerruysUNKNOWN Arterial Revascularization Therapies Study Group
Jun 5, 2001·Nature Reviews. Genetics·J Flint, R Mott
Jul 12, 2001·Annual Review of Biomedical Engineering·A Marziali, M Akeson
Sep 5, 2001·Progress in Cardiovascular Diseases·G M Lanza, S A Wickline
Jan 15, 2002·Cardiology Clinics·F G Blankenberg, H W Strauss
May 29, 2002·Tissue Engineering·Arthur H WongMichael D Dake
Jul 19, 2002·American Journal of Physiology. Heart and Circulatory Physiology·Afaf AbsoodLinda M Graham
Oct 16, 2002·Arteriosclerosis, Thrombosis, and Vascular Biology·Joseph J BoyleMartin R Bennett
Oct 16, 2002·Arteriosclerosis, Thrombosis, and Vascular Biology·Youichiro WadaTatsuhiko Kodama
Dec 3, 2002·Science·Benoit DubertretAlbert Libchaber
Jan 10, 2003·Analytical and Bioanalytical Chemistry·Sofia Sotiropoulou, Nikolas A Chaniotakis
Feb 13, 2003·Circulation·Ariel FinkelsteinNeal L Eigler
Mar 13, 2003·Journal of Vascular and Interventional Radiology : JVIR·William C CulpMohammed Moursi
Apr 1, 2003·Advances in Experimental Medicine and Biology·Tanihiro YoshimotoTadashi Tanabe
Feb 1, 1955·Archives of Biochemistry and Biophysics·R ALTSCHULJ D STEPHEN
Nov 26, 2003·European Cells & Materials·T C Flanagan, A Pandit
Dec 6, 2003·Circulation·Denis B BuxtonUNKNOWN National Heart, Lung, and Blood Institute Nanotechnology Working Group
Apr 28, 2004·Advanced Drug Delivery Reviews·Evan C UngerReena Zutshi
May 15, 2004·American Journal of Physiology. Heart and Circulatory Physiology·Afaf AbsoodLinda M Graham

❮ Previous
Next ❯

Citations

Sep 17, 2010·Cardiovascular and Interventional Radiology·Sarah PowerMichael J Lee
Aug 16, 2012·Pediatric Surgery International·K K Y Wong, X L Liu
Aug 19, 2011·Applied Biochemistry and Biotechnology·Mainak ChakrabortyVibha Rani
Jul 31, 2013·Biomaterials·Daniel R LewisPrabhas V Moghe
Jun 3, 2008·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Robert J Gropler
May 14, 2009·Expert Review of Molecular Diagnostics·Jian-Ming LüChangyi Chen
Apr 28, 2011·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Daniel R LewisPrabhas V Moghe
Jan 15, 2014·Biomaterials·Christa L Modery-Pawlowski, Anirban Sen Gupta
Jul 6, 2016·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Marcela Frota CavalcanteDulcineia Saes Parra Abdalla
Mar 5, 2016·International Journal of Molecular Sciences·Menka KhoobchandaniKattesh V Katti
Sep 7, 2017·Nature Nanotechnology·Morteza MahmoudiOmid C Farokhzad
Dec 3, 2015·Microscopy Research and Technique·Gamze Doğanİpek Erdoğan
Dec 21, 2011·Journal of Biomaterials Science. Polymer Edition·A ObermeierR Burgkart

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Advanced Imaging of Cellular Signaling

Cell signaling is a vital mechanism for communication within cells and outside with the environment. Several different signaling pathways have been found and advanced imaging techniques are being developed to visualize the molecules involved in these signaling pathways. Find the latest research in advanced imaging of cellular signaling here.

Related Papers

IUBMB Life
Erez Koren, Vladimir P Torchilin
Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology
Denis B Buxton
Nanomedicine : Nanotechnology, Biology, and Medicine
Anirban Sen Gupta
European Journal of Immunology
Alberto MantovaniMassimo Locati
Arteriosclerosis, Thrombosis, and Vascular Biology
Alberto MantovaniMassimo Locati
© 2021 Meta ULC. All rights reserved