PMID: 6399308Jan 1, 1984Paper

Converging projections of hydromineral imbalances and hormonal co-action upon neurons surrounding the anterior wall of the third ventricle

Journal of Physiology, Paris
S Nicolaidis, A Jeulin

Abstract

Various structures have been found in the anterior third periventricular area (A3pV) which seem to be concerned with hydromineral imbalances, since they contain neurons which can sense changes in osmolality, blood volume, blood pressure, angiotensin II [Ang II] levels and temperature. These neurons also seem to be concerned with the setting in action of corrective responses at an autonomic or behavioural level. The discovery of neurons in this area that respond to more than one signal (for example osmotic and volaemic, or blood pressure and Ang II levels) suggested that this area has an integrative role. More recent findings from stimulation and lesion experiments have shown that the broadly inter-connected A3pV structures which extend from the region of the suprachiasmatic nucleus to the subfornical organ (SFO), are targets for many stimuli. Our recent electrophysiological data have strengthened the idea of an integrative role for A3pV structures. Iontophoretic application of various substances has shown that a single baro-sensitive neuron can have its firing modulated by Ang II. In the present paper we report the discovery of A3pV neurons which respond to both Ang II and vasopressin (VP). Furthermore the co-action of these tw...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.