Conversion of M serotype 24 of Streptococcus pyogenes to M serotypes 5 and 18: effect on resistance to phagocytosis and adhesion to host cells.

Infection and Immunity
H S CourtneyD L Hasty

Abstract

In this study, we utilized recombinant strains expressing the M5 and M18 proteins and M- mutants of group A streptococci to compare the abilities of these M proteins to confer resistance to phagocytosis and to mediate adhesion to host cells. The data indicate that the M5 and M18 proteins can confer resistance to phagocytosis, that fibrinogen is required for this resistance, and that these M proteins can mediate adhesion to HEp-2 cells.

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Citations

Feb 26, 2000·Infection and Immunity·G L DarmstadtC E Rubens
Jan 20, 2006·Molecular Microbiology·Harry S CourtneyJames B Dale
Apr 4, 2014·Clinical Microbiology Reviews·Mark J WalkerVictor Nizet
Oct 1, 2014·The Journal of Biological Chemistry·Anna HenninghamJason N Cole
Oct 18, 2000·The Journal of Clinical Investigation·C CywesM R Wessels
May 25, 2004·Infection and Immunity·Heike GutekunstDieter J Reinscheid
Jun 22, 1999·Immunologic Research·E R Brandt, M F Good
Jun 18, 2016·FEBS Letters·Stephan BrouwerMark J Walker
Mar 6, 1999·Microbiology and Molecular Biology Reviews : MMBR·W W Navarre, O Schneewind
Mar 20, 1999·Infection and Immunity·B M KihlbergL Björck
Mar 30, 2010·Trends in Microbiology·Pierre R SmeestersKadaba S Sriprakash

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