Conversion Percentage of Tryptophan to Nicotinamide is Higher in Rice Protein Diet than in Wheat Protein Diet in Rats

International Journal of Tryptophan Research : IJTR
Katsumi ShibataTomoyo Kawamura

Abstract

We reported previously that the pellagragenic property of corn protein is not only low l-tryptophan concentration but also the lower conversion percentage of l-tryptophan to nicotinamide; the amino acid composition greatly affected the conversion percentage. The amino acid value of wheat protein is lower than that of rice protein. In the present study, we compare the conversion percentages of l-tryptophan to nicotinamide between wheat protein and rice protein diets in growing rats. The body weight gain for 28 days in rats fed with a 10% amino acid mixture diet with wheat protein was lower than that of rats fed with a 10% amino acid diet with rice protein (68.1 ± 1.6 g vs 108.4 ± 1.9 g; P < 0.05). The conversion percentage of l-tryptophan to nicotinamide was also lower for the wheat protein diet compared with the rice protein diet (1.44 ± 0.036% vs 2.84 ± 0.19%; P < 0.05). The addition of limiting amino acids (l-isoleucine, l-lysine, l-tryptophan, l-methionine, l-threonine) to the wheat protein diet improved growth and the conversion percentage. In conclusion, our result supports the thinking that the composition of amino acids affects the conversion ratio of l-tryptophan to nicotinamide.

References

Apr 1, 1978·The American Journal of Clinical Nutrition·D F Miller
May 1, 1976·The Journal of Nutrition·Y Itokawa
May 1, 1997·The Journal of Nutrition·P G Reeves
Nov 1, 1964·The American Journal of Clinical Nutrition·G R JANSEN, E E HOWE
Sep 1, 1951·The Journal of Nutrition·J LAGUNA, K J CARPENTER
May 18, 2005·Journal of Nutritional Science and Vitaminology·Tsutomu FtukijwatariKatsumi Shibata

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