Converting venous acid-base and oxygen status to arterial in patients with lung disease

The European Respiratory Journal
Stephen E ReesH Harving

Abstract

The aim of the present study was to evaluate a method for calculating arterial values of pH, carbon dioxide tension (P(CO(2))) and oxygen tension (P(O(2))) from peripheral venous values. In total, 40 patients were studied. Arterial and peripheral venous blood were sampled at a department of respiratory diseases. Arterial values were calculated from venous, and measured and calculated values of arterial pH, P(CO(2)) and P(O(2)) were compared. Measured and calculated values of pH and P(CO(2)) correlated well, with the difference between them having a very small bias and standard deviation (pH -0.001+/-0.013, P(CO(2)) -0.09+/-0.28 kPa) within those considered acceptable for laboratory equipment and clinical practice. All but four patients had peripheral oxygen saturation (S(p,O(2))) <or=96%, and for these measured and calculated P(O(2)) correlated well, with a difference such that the bias and standard deviation suggested that calculated P(O(2)) may be clinically useful (P(O(2)) 0.11+/-0.53 kPa). The present study evaluates a method for calculating arterial pH, carbon dioxide tension and oxygen tension from venous blood. It has been shown that arterial pH and carbon dioxide tension can be calculated precisely, and that oxygen tens...Continue Reading

Citations

Sep 22, 2011·ClinicoEconomics and Outcomes Research : CEOR·Lars OddershedeLars Ehlers
Sep 13, 2012·Critical Care Research and Practice·Eric KipnisRonan Thibault
Oct 25, 2012·Clinical Chemistry and Laboratory Medicine : CCLM·Stephen E ReesSøren R Kristensen
Feb 18, 2021·Journal of the American Medical Informatics Association : JAMIA·Alan H MorrisDonald Berwick
Mar 14, 2021·Computer Methods and Programs in Biomedicine·Lisha ShastriLars Pilegaard Thomsen

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