Cooling-rate dependent single-crystal-to-single-crystal phase transition in an organic co-crystal

Chemical Communications : Chem Comm
Adam W CrawfordKristin M Hutchins

Abstract

We investigate a previously unobserved phase transition in an organic co-crystal containing the olefin trans-1,2-bis(4-pyridyl)ethylene. The olefin undergoes molecular motion in the crystalline state, and converts from a disordered to ordered phase upon cooling. Ordering causes a unit cell change to occur via a reversible single-crystal-to-single-crystal (SCSC) transformation. The ordered phase is only accessed via slow cooling; flash cooling locks the crystal in a kinetically trapped, disordered state, and SCSC reversibility is lost. The common practice of flash cooling may inhibit access to thermodynamic products and unique phases.

References

Nov 1, 2001·Journal of the American Chemical Society·J Harada, K Ogawa
Jul 23, 2009·Chemical Society Reviews·Jun Harada, Keiichiro Ogawa
May 26, 2017·Angewandte Chemie·Manas K PandaPanče Naumov
Jul 14, 2017·Chemical Communications : Chem Comm·Abdullah KhalilPanče Naumov
Oct 6, 2017·Acta Crystallographica Section B, Structural Science, Crystal Engineering and Materials·Tze Shyang Chia, Ching Kheng Quah
Mar 29, 2018·Chemical Communications : Chem Comm·Agnieszka JaniakLeonard J Barbour
Nov 30, 2018·Chemical Communications : Chem Comm·C A Gunawardana, C B Aakeröy

❮ Previous
Next ❯

Citations

Jan 18, 2020·IUCrJ·Khushboo YadavaJagadese J Vittal
Jul 17, 2019·Journal of the American Chemical Society·Isabella E ClaassensDelia A Haynes
Dec 31, 2020·Journal of the American Chemical Society·Rohit BhowalDeepak Chopra
Nov 24, 2021·Journal of the American Chemical Society·Olivier RenierAnja-Verena Mudring

❮ Previous
Next ❯

Methods Mentioned

BETA
X-ray
differential scanning calorimetry

Software Mentioned

PASCal

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.