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Coordinated Evolution of Influenza A Surface Proteins

bioRxiv

Aug 20, 2014

Alexey D. NeverovGeorgii A. Bazykin

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Abstract

Surface proteins hemagglutinin (HA) and neuraminidase (NA) of the human influenza A virus evolve under selection pressure to escape the human adaptive immune response and antiviral drug treatments. In addition to these external selection pressures, some mutations in HA are known to affe...read more

Mentioned in this Paper

Landscapes
Cold Hemagglutinin Disease
Gene Mutation
Neuraminidase
Influenza virus vaccine
Hyaluronic Acid
Genome
Antiviral Agents
Oseltamivir
Epistasis, Genetic
13
12
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  • Coordinated Evolution of Influenza A Surface Proteins

    bioRxiv

    Aug 20, 2014

    Alexey D. NeverovGeorgii A. Bazykin

    PMID: 990008235

    DOI: 10.1101/008235

    Abstract

    Surface proteins hemagglutinin (HA) and neuraminidase (NA) of the human influenza A virus evolve under selection pressure to escape the human adaptive immune response and antiviral drug treatments. In addition to these external selection pressures, some mutations in HA are known to affe...read more

    Mentioned in this Paper

    Landscapes
    Cold Hemagglutinin Disease
    Gene Mutation
    Neuraminidase
    Influenza virus vaccine
    13
    12

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