Copeptin levels in patients with coronary artery ectasia

Interventional Medicine & Applied Science
Ozkan YavcinMustafa Necati Dagli

Abstract

The etiology and pathophysiology of coronary artery ectasia (CAE) has not been fully elucidated. A rapid rise in plasma copeptin has been observed in cardiovascular diseases, stroke, sepsis, and shock. This increase has diagnostic and prognostic value. The aim of this study was to investigate whether copeptin has a relationship with CAE. This observational prospective study was carried out between October 2012 and March 2013 in the cardiology catheter laboratory with the inclusion of 44 subjects with a diagnosis of CAE and 44 age- and gender-matched individuals with normal coronary arteries. Blood samples obtained from the patients were stored at -70 °C until analysis and copeptin levels in sera were measured by ELISA. This study comprised 88 study participants, among whom 44 were patients meeting ectasia criteria [mean age: 58.0 ± 11.5 years; 59% (n = 26) male], and 44 were control subjects with angiographically normal coronary anatomy [mean age: 49.2 ± 10.1 years; 30% (n = 13) male]. Copeptin levels were similar between the groups (p > 0.05). In addition, there was no correlation between copeptin levels and CAE. In this study, it is examined that copeptin levels were not elevated in CAE patients.

References

Feb 1, 1976·The American Journal of Cardiology·J E MarkisR Gorlin
Dec 15, 1991·The American Journal of Cardiology·E J GussenhovenN Bom
Oct 1, 1985·British Heart Journal·G G HartnellR B Pridie
Nov 7, 1999·Journal of the American College of Cardiology·D KrügerA Sheikhzadeh
May 10, 2003·Revista española de cardiología·Eduardo Pinar BermúdezMariano Valdés Chávarri
Feb 24, 2006·Cardiology·Hale YilmazAydin Cagil
Jan 16, 2007·Medical Hypotheses·Jian-Jun LiJie Li
Apr 25, 2007·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Ertan Yetkin, Johannes Waltenberger
Apr 17, 2008·Cardiology in Review·Michael P ChrissoherisAndre Ghantous
Aug 13, 2008·International Journal of Cardiology·Antonios P AntoniadisGeorge D Giannoglou
Apr 2, 2009·Heart and Vessels·San Bao ChaiChao Shu Tang
Jun 27, 2009·Journal of the American College of Cardiology·Tobias ReichlinChristian Mueller
Aug 7, 2010·Congestive Heart Failure·Nils G Morgenthaler
Jan 31, 2012·International Journal of Cardiology·Stephan von HaehlingBoris Bigalke
May 23, 2014·Current Atherosclerosis Reports·Martin Möckel, Julia Searle
Mar 31, 2015·American Heart Journal·Sofia EnhörningOlle Melander

❮ Previous
Next ❯

Methods Mentioned

BETA
ELISA

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Angiology
Kosmas I ParaskevasAriadne Malamitsi-Puchner
Journal of Cardiovascular Medicine
Beata Morawiec, Damian Kawecki
Stress : the International Journal on the Biology of Stress
Sandrine A UrwylerMirjam Christ-Crain
Expert Review of Cardiovascular Therapy
Nicholas A Marston, Alan S Maisel
© 2021 Meta ULC. All rights reserved