COPPADIS-2015 (COhort of Patients with PArkinson's DIsease in Spain, 2015), a global--clinical evaluations, serum biomarkers, genetic studies and neuroimaging--prospective, multicenter, non-interventional, long-term study on Parkinson's disease progression

BMC Neurology
Diego Santos-GarcíaCOPPADIS Study Group

Abstract

Parkinson's disease (PD) is a progressive neurodegenerative disorder causing motor and non-motor symptoms that can affect independence, social adjustment and the quality of life (QoL) of both patients and caregivers. Studies designed to find diagnostic and/or progression biomarkers of PD are needed. We describe here the study protocol of COPPADIS-2015 (COhort of Patients with PArkinson's DIsease in Spain, 2015), an integral PD project based on four aspects/concepts: 1) PD as a global disease (motor and non-motor symptoms); 2) QoL and caregiver issues; 3) Biomarkers; 4) Disease progression. Observational, descriptive, non-interventional, 5-year follow-up, national (Spain), multicenter (45 centers from 15 autonomous communities), evaluation study. Specific goals: (1) detailed study (clinical evaluations, serum biomarkers, genetic studies and neuroimaging) of a population of PD patients from different areas of Spain, (2) comparison with a control group and (3) follow-up for 5 years. COPPADIS-2015 has been specifically designed to assess 17 proposed objectives. approximately 800 non-dementia PD patients, 600 principal caregivers and 400 control subjects. Study evaluations: (1) baseline includes motor assessment (e.g., Unified Parki...Continue Reading

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Dec 1, 1989·The Gerontologist·M Novak, C Guest
May 1, 1967·Neurology·M M Hoehn, M D Yahr
May 1, 1983·Journal of Gerontology·B C Robinson
May 19, 2000·Parkinsonism & Related Disorders·N GiladiA D Korczyn
Jun 14, 2002·Behavior Research Methods, Instruments, & Computers : a Journal of the Psychonomic Society, Inc·John T E Richardson, Tomaso Vecchi
Nov 20, 2002·Journal of Neurology, Neurosurgery, and Psychiatry·K R ChaudhuriC Trenkwalder
Mar 20, 2003·Microscopy Research and Technique·Matthias RothermundtVolker Arolt
Nov 20, 2004·Movement Disorders : Official Journal of the Movement Disorder Society·Mariese A HelyRobert Trafficante
Dec 28, 2004·Parkinsonism & Related Disorders·Débora V SchafCarlos R M Rieder
Oct 8, 2005·Movement Disorders : Official Journal of the Movement Disorder Society·Laura MarshUNKNOWN NINDS/NIMH Work Group on Depression and Parkinson's Disease
Nov 8, 2005·Parkinsonism & Related Disorders·Anette SchragMarjan Jahanshahi
Jul 6, 2006·Journal of Neurology, Neurosurgery, and Psychiatry·D AarslandJ L Cummings
Aug 4, 2007·Movement Disorders : Official Journal of the Movement Disorder Society·Kallol Ray ChaudhuriAnthony H V Schapira
Dec 22, 2007·Movement Disorders : Official Journal of the Movement Disorder Society·Bruno DuboisMurat Emre
Mar 18, 2008·Journal of Neurology, Neurosurgery, and Psychiatry·J Jankovic
Apr 3, 2008·Movement Disorders : Official Journal of the Movement Disorder Society·Javier PagonabarragaAlexandre Gironell
Apr 17, 2008·Archives of Neurology·Michael A SchwarzschildJohn Ondrasik
Jun 27, 2008·Neurology·R KatzenschlagerUNKNOWN Parkinson's Disease Research Group of the United Kingdom
Aug 2, 2008·Parkinsonism & Related Disorders·M DufekI Rektor
Aug 6, 2008·Brain, Behavior, and Immunity·M RealeM Onofrj
Aug 19, 2008·Movement Disorders : Official Journal of the Movement Disorder Society·Pablo Martinez-MartinUNKNOWN Longitudinal Parkinson's Disease Patient Study (Estudio longitudinal de pacientes con enfermedad de Parkinson-ELEP) Group
Mar 3, 2009·Neurology·Eduardo TolosaYaroslau Compta
Mar 20, 2009·Human Molecular Genetics·Suzanne Lesage, Alexis Brice
May 9, 2009·Movement Disorders : Official Journal of the Movement Disorder Society·Holger HonigK Ray Chaudhuri
May 20, 2009·Movement Disorders : Official Journal of the Movement Disorder Society·Daniel WeintraubValerie Voon
Dec 17, 2009·Movement Disorders : Official Journal of the Movement Disorder Society·Esther CuboUNKNOWN ELEP Group Members
Feb 27, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·Blair Ford
Jun 29, 2010·Annals of Neurology·Cory TothOksana Suchowersky
Oct 15, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·Huijuan LiQing Wang
Feb 2, 2011·Movement Disorders : Official Journal of the Movement Disorder Society·Oliver H H GerlachWim E J Weber
Jun 15, 2011·Brain : a Journal of Neurology·Aristide MerolaLeonardo Lopiano
Aug 26, 2011·Journal of the Neurological Sciences·Naroa Ibarretxe-BilbaoEduardo Tolosa
Sep 21, 2011·Progress in Neurobiology·UNKNOWN Parkinson Progression Marker Initiative
Nov 2, 2011·Movement Disorders : Official Journal of the Movement Disorder Society·Klaus SeppiCristina Sampaio
Nov 10, 2011·Neuroepidemiology·Monika Balzer-GeldsetzerRichard Dodel
Feb 3, 2012·Parkinsonism & Related Disorders·Yen-Yu ChenChien-Hsu Lai
Mar 1, 2012·Journal of Neurology, Neurosurgery, and Psychiatry·Man AuyeungE Yeung
Mar 1, 2012·Neurochemical Research·Gulizar MadenciFikri Ak
Mar 22, 2012·Therapeutic Advances in Neurological Disorders·Pablo Martinez-Martin, Mónica M Kurtis
Apr 18, 2012·Movement Disorders : Official Journal of the Movement Disorder Society·C Warren Olanow, José A Obeso
May 16, 2012·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Neusa Sica da RochaMarcelo P Fleck

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Citations

Mar 4, 2017·Nature Reviews. Neurology·Dag AarslandClive Ballard
Jan 20, 2017·Current Neurology and Neuroscience Reports·Shen-Yang LimSoon Chai Low
Jul 27, 2017·Journal of Geriatric Psychiatry and Neurology·Philip E MosleyNadeeka Dissanayaka
Jun 11, 2019·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·D Santos GarcíaUNKNOWN COPPADIS Study Group
Sep 30, 2020·Brain Imaging and Behavior·Xia-An BiUNKNOWN Alzheimer’s Disease Neuroimaging Initiative
Aug 20, 2020·Acta Neurologica Scandinavica·Daniel J van WamelenUNKNOWN International Parkinson and Movement Disorder Society Parkinson's Disease Non-Motor Study Group
Mar 18, 2020·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·D Santos-GarcíaD McAfee
Apr 26, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Diego Santos-GarcíaUNKNOWN COPPADIS Study Group
Dec 6, 2018·Revista brasileira de enfermagem·Maria Fernanda Baeta Neves Alonso da CostaGraziela De Luca Canto
Nov 14, 2018·Frontiers in Aging Neuroscience·Geraldine HippRejko Krüger
Nov 2, 2019·Journal of Neural Transmission·Diego Santos-GarcíaUNKNOWN COPPADIS Study Group
Oct 13, 2020·Journal of Geriatric Psychiatry and Neurology·Diego Santos-GarcíaP Martinez-Martin
Aug 4, 2020·Journal of Parkinson's Disease·Esther CuboUNKNOWN Coppadis Study Group:
Nov 11, 2020·International Journal of Geriatric Psychiatry·Diego Santos-GarcíaUNKNOWN COPPADIS Study Group
Apr 13, 2021·Journal of Parkinson's Disease·Diego Santos GarcíaUNKNOWN COPPADIS Study Group

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Methods Mentioned

BETA
exome sequencing

Software Mentioned

EUROHIS
COPPADIS
QOL

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