Copper-catalysed ortho-selective C-H bond functionalization of phenols and naphthols with α-aryl-α-diazoesters

Chemical Communications : Chem Comm
Ben MaLu Liu

Abstract

Herein, we reported the first copper-catalyzed highly efficient C(sp2)-H functionalization of unprotected naphthols and phenols with α-aryl-α-diazoesters. In this transformation, CuCl2 efficiently promoted the highly chemo- and site-selective C-H bond functionalization under mild conditions, furnishing diverse phenol derivatives in moderate to excellent yields from readily available starting materials.

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Citations

Feb 9, 2021·Chemical Reviews·Chetan C ChintawarNitin T Patil
May 25, 2021·Organic & Biomolecular Chemistry·So Won Youn, Cheon-Gyu Cho
Jun 18, 2021·Organic & Biomolecular Chemistry·Yangyang ZhangJun Jiang
Jun 23, 2021·Organic & Biomolecular Chemistry·Zhiqiong TangLu Liu
Nov 3, 2021·The Journal of Organic Chemistry·Neha ChalotraBhahwal Ali Shah

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