Copper-catalyzed aerobic cascade cycloamination and acyloxylation: a direct approach to 4-acyloxy-1H-pyrazoles

Organic & Biomolecular Chemistry
Zhengwei DingBin Xu

Abstract

A novel direct transformation of hydrazones to acyloxylated pyrazoles by copper-catalyzed regioselective olefinic C(sp(2))-H bond cycloamination and acyloxylation was performed under mild conditions, which combines the formation of the pyrazole skeleton and installation of an acyloxyl group in a single step, using facile carboxylic acids as the acyloxylation reagents.

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Citations

May 28, 2016·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Mingchun Gao, Bin Xu

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