Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines.

Chemical Communications : Chem Comm
Joshua J SmithHon Wai Lam

Abstract

Cu-catalyzed three-component couplings of vinylazaarenes, B2(pin)2, and N-Boc imines are described. Oxidation of the initially formed boronate gives azaarene-containing, Boc-protected amino alcohols with reasonable to good diastereoselectivities.

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Jul 20, 2016·Chemical Reviews·Emily C NeeveTodd B Marder
Aug 30, 2017·Angewandte Chemie·Yuan HuangM Kevin Brown
Feb 13, 2018·Chemistry, an Asian Journal·DingXi LiJaesook Yun
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Jun 17, 2020·Angewandte Chemie·Fabien TalbotDavid John Procter
May 5, 2020·Beilstein Journal of Organic Chemistry·Balaram S TakaleBruce H Lipshutz
May 7, 2019·Chemical Science·Maxime KlausenMireille Blanchard-Desce
Jan 16, 2020·Chemical Communications : Chem Comm·Ya-Li ZengQuan-Zhong Liu
Feb 21, 2018·Organic Letters·Bin ChenJian Liao
Jan 11, 2018·Journal of the American Chemical Society·Xingyu JiangJohn F Hartwig
Oct 8, 2021·Chemical Reviews·Shubhankar Kumar BoseTodd B Marder

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