Copper-Catalyzed Direct Sulfoximination of Heteroaromatic N-Oxides by Dual C-H/N-H Dehydrogenative Cross-Coupling

Chemistry, an Asian Journal
Hao YuCarsten Bolm

Abstract

A dual C-H/N-H dehydrogenative coupling of quinoline-type N-oxides with sulfoximines that leads to N-(hetero)arylsulfoximines in high yields has been realized by using a catalytic amount of CuBr in air. The method does not require any additional ligand, base, reactivity modifier or oxidant and provides a practical route towards a series of sulfoximidoyl-functionalized quinolines and derivatives.

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Citations

Jul 6, 2016·Organic Letters·Ramona PirwerdjanCarsten Bolm
Jan 5, 2017·Chemical Reviews·Yoonsu ParkSukbok Chang
Apr 27, 2017·Chemical Reviews·Kei MurakamiKenichiro Itami
Oct 10, 2019·Organic & Biomolecular Chemistry·Chenna Reddy M LVadivelu Saravanan
Nov 20, 2019·Dalton Transactions : an International Journal of Inorganic Chemistry·Yangjuan LiYu Gong
Mar 18, 2021·Beilstein Journal of Organic Chemistry·Geetanjali S SontakkeChandra M R Volla
Aug 8, 2017·The Journal of Organic Chemistry·Aniruddha BiswasRajarshi Samanta

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