Copper-catalyzed N-methylation/ethylation of sulfoximines

Organic & Biomolecular Chemistry
Fan TengJin-Tao Yu

Abstract

A protocol for the copper-catalyzed N-methylation of sulfoximines with di-tert-butyl peroxide (DTBP) was developed. This protocol has good functional group tolerance leading to N-methylated sulfoximines in moderate to good yields. Besides, N-ethylation of sulfoximines was achieved in the presence of bis(1,1-dimethylpropyl)peroxide as the ethylating agent under a standard procedure.

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Citations

Oct 7, 2015·Organic & Biomolecular Chemistry·Haibo PengJiang Cheng
Oct 7, 2016·Chemical Communications : Chem Comm·Hui ZhuJiang Cheng
Oct 18, 2018·Chemistry : a European Journal·Yantao Chen
Jan 31, 2017·Chemical Communications : Chem Comm·Jean-François LohierVincent Reboul
Sep 15, 2018·Nature Communications·Xu BaoJieping Zhu
Sep 28, 2017·Organic & Biomolecular Chemistry·Surabhi GuptaJeyakumar Kandasamy
May 19, 2021·The Journal of Organic Chemistry·Gregory B CravenAlan Armstrong
Mar 17, 2020·Organic Letters·Priscilla Mendonça MatosRobert A Stockman
Jun 8, 2018·Organic Letters·Priscilla Mendonça MatosRobert A Stockman

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