Copper-Catalyzed Oxidative Cross-Coupling of Electron-Deficient Polyfluorophenylboronate Esters with Terminal Alkynes.

Chemistry : a European Journal
Zhiqiang LiuTodd B Marder

Abstract

We report herein a mild procedure for the copper-catalyzed oxidative cross-coupling of electron-deficient polyfluorophenylboronate esters with terminal alkynes. This method displays good functional group tolerance and broad substrate scope, generating cross-coupled alkynyl(fluoro)arene products in moderate to excellent yields. Thus, it represents a simple alternative to the conventional Sonogashira reaction.

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Citations

Nov 27, 2020·Chemistry : a European Journal·Steffen A FöhrenbacherUdo Radius
Feb 16, 2021·Chemical Communications : Chem Comm·Fabian SchorrHolger Braunschweig
Oct 8, 2021·Chemical Reviews·Shubhankar Kumar BoseTodd B Marder

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