Copper-catalyzed oxidative C(sp(3))-H/N-H coupling of sulfoximines and amides with simple alkanes via a radical process

Chemical Communications : Chem Comm
Fan TengJiang Cheng

Abstract

A copper-catalyzed oxidative C(sp(3))-H/N-H coupling of sulfoximines with simple alkanes was developed. This protocol involved C(sp(3))-N bond formation via a radical pathway and tolerated a series of functional groups, such as chloro, methyl and aryl, on the phenyl rings. Apart from sulfoximines, amides, saccharin and aniline also worked well to give the corresponding N-alkylated products.

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Citations

Oct 7, 2015·Organic & Biomolecular Chemistry·Haibo PengJiang Cheng
Sep 4, 2015·Organic & Biomolecular Chemistry·Fan TengJin-Tao Yu
Feb 13, 2016·Chemical Society Reviews·Xu Zhu, Shunsuke Chiba
Oct 7, 2016·Chemical Communications : Chem Comm·Hui ZhuJiang Cheng
Apr 27, 2018·Organic & Biomolecular Chemistry·Rongzhen ChenJiang Cheng
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May 23, 2019·Angewandte Chemie·Dirk Leifert, Armido Studer
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Feb 20, 2020·Chemistry : a European Journal·Kanako Nozawa-KumadaYoshinori Kondo
Dec 8, 2016·Organic & Biomolecular Chemistry·Arghya BanerjeeBhisma K Patel
Jan 31, 2017·Chemical Communications : Chem Comm·Jean-François LohierVincent Reboul
May 19, 2021·The Journal of Organic Chemistry·Gregory B CravenAlan Armstrong
Jun 18, 2021·Chemical Communications : Chem Comm·Han LiuChangduo Pan
Feb 20, 2019·The Journal of Organic Chemistry·Song LiuYu Lan
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Jun 8, 2018·Organic Letters·Priscilla Mendonça MatosRobert A Stockman
Aug 14, 2021·Chemistry : a European Journal·Subrata K GhoshRobert J Comito

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