Copper-Catalyzed Synthesis of Activated Sulfonate Esters from Boronic Acids, DABSO, and Pentafluorophenol

Organic Letters
Vincent VedovatoMichael C Willis

Abstract

The synthesis of pentafluorophenyl (PFP) sulfonate esters based on the Pd-catalyzed sulfination of aryl and heteroaryl boronic acids is reported. The sulfinate intermediates are converted in situ to the corresponding sulfonate esters using a copper-catalyzed oxidative process, providing a broad range of PFP esters in good yields.

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Citations

Oct 24, 2018·Chemical Communications : Chem Comm·Guanyinsheng QiuJie Wu
Jan 3, 2019·Chemical Communications : Chem Comm·Shengqing YeJie Wu
Feb 1, 2019·Chemical Communications : Chem Comm·Shengqing YeGuanyinsheng Qiu

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