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Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice

Atherosclerosis

Jul 10, 2012

Hao WeiBalz Frei

Abstract

Endothelial activation, which is characterized by upregulation of cellular adhesion molecules and pro-inflammatory chemokines and cytokines, and consequent monocyte recruitment to the arterial intima are etiologic factors in atherosclerosis. Redox-active transition metal ions, such as c...read more

Mentioned in this Paper

Oxidized Low Density Lipoprotein Measurement
Eosinophil
ISYNA1 gene
Biochemical Pathway
Hypocupremia
Necrosis
Vascular Inflammations
Xanthine
Entire Descending Aorta
Systemic Inflammatory Response Syndrome
25
Paper Details
References
  • References16
  • Citations13
12
  • References16
  • Citations13
12

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Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice

Atherosclerosis

Jul 10, 2012

Hao WeiBalz Frei

PMID: 22770994

DOI: 10.1016/j.atherosclerosis.2012.06.013

Abstract

Endothelial activation, which is characterized by upregulation of cellular adhesion molecules and pro-inflammatory chemokines and cytokines, and consequent monocyte recruitment to the arterial intima are etiologic factors in atherosclerosis. Redox-active transition metal ions, such as c...read more

Mentioned in this Paper

Oxidized Low Density Lipoprotein Measurement
Eosinophil
ISYNA1 gene
Biochemical Pathway
Hypocupremia
Necrosis
Vascular Inflammations
Xanthine
Entire Descending Aorta
Systemic Inflammatory Response Syndrome
25

Similar Papers Found In These Feeds

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Paper Details
References
  • References16
  • Citations13
12
  • References16
  • Citations13
12
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