Copper containing intra-uterine devices versus depot progestogens for contraception

The Cochrane Database of Systematic Reviews
G J HofmeyrT A Lawrie


Highly effective contraception is essential to reduce unintended pregnancies and the effect these have on individuals, society and public health resources. Intrauterine devices (IUDs) and depot progestogens are two commonly used long-acting, reversible contraceptive methods with different risk and benefit profiles. To compare the contraceptive and non-contraceptive benefits and risks of using the copper-containing IUD versus depot progestogens for contraception. In June 2009 we searched the Cochrane Pregnancy and Childbirth Group Trials Register, the Cochrane Central Register of Controlled Trials, Pubmed, Popline, Clinical, the Current Controlled Trials metaRegister, EMBASE and LILACS, and contacted study authors. Randomized trials comparing women using copper-containing IUDs with women using depot progestogens. We assessed eligibility and trial quality, extracted and double-entered data. Two studies were included in the review. In the one study in HIV infected women, the IUD was compared with depot progestogen or the oral contraceptive, according to the women's choice. As the majority of women chose depot progestogen, we have included this study in the review, within a mixed hormonal contraception sub-group.Overall,...Continue Reading


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