Copper-mediated oxidative cross-coupling reaction of terminal alkynes with α-silyldifluoromethylphosphonates: an efficient method for α,α-difluoropropargylphosphonates

Organic Letters
Xueliang JiangFeng-Ling Qing

Abstract

A copper-mediated oxidative cross-coupling reaction of terminal alkynes with readily available α-silyldifluoromethylphosphonates under mild conditions has been developed. This method allows for an efficient synthesis of a series of synthetically useful α,α-difluoropropargylphosphonates with excellent functional group compatibility.

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Citations

Jun 24, 2016·Chemistry : a European Journal·Maria V IvanovaThomas Poisson
Dec 18, 2015·Organic & Biomolecular Chemistry·Subhajit MishraAlakananda Hajra
Nov 15, 2018·Organic & Biomolecular Chemistry·Naila IqbalEun Jin Cho
Jul 17, 2015·Chemistry : a European Journal·Marie-Charlotte BelhommeXavier Pannecoucke
Jan 13, 2017·Angewandte Chemie·Xingliang NieGangguo Zhu
Sep 26, 2017·Chemistry : a European Journal·Maria V IvanovaThomas Poisson
Jul 15, 2016·Angewandte Chemie·Jian-Heng YeDa-Gang Yu
Apr 21, 2018·Chemical Science·Guojiao Wu, Axel Jacobi von Wangelin
Jul 18, 2012·Journal of the American Chemical Society·Chao ChenFeng-Ling Qing
Mar 22, 2013·The Journal of Organic Chemistry·Romana Pajkert, Gerd-Volker Röschenthaler

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