Copper-Mediated Polymerization without External Deoxygenation or Oxygen Scavengers

Angewandte Chemie
Evelina LiarouDavid M Haddleton

Abstract

As a method for overcoming the challenge of rigorous deoxygenation in copper-mediated controlled radical polymerization processes [e.g., atom-transfer radical polymerization (ATRP)], reported here is a simple Cu0 -RDRP (RDRP=reversible deactivation radical polymerization) system in the absence of external additives (e.g., reducing agents, enzymes etc.). By simply adjusting the headspace of the reaction vessel, a wide range of monomers, namely acrylates, methacrylates, acrylamides, and styrene, can be polymerized in a controlled manner to yield polymers with low dispersities, near-quantitative conversions, and high end-group fidelity. Significantly, this approach is scalable (ca. 125 g), tolerant to elevated temperatures, compatible with both organic and aqueous media, and does not rely on external stimuli which may limit the monomer pool. The robustness and versatility of this methodology is further demonstrated by the applicability to other copper-mediated techniques, including conventional ATRP and light-mediated approaches.

References

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Citations

Oct 18, 2018·Angewandte Chemie·Alan E EncisoKrzysztof Matyjaszewski
Oct 31, 2018·Macromolecular Rapid Communications·Thomas G RibelliKrzysztof Matyjaszewski
Sep 4, 2019·Angewandte Chemie·Liwen ZhangCyrille Boyer
Aug 28, 2019·Chemical Science·Richard WhitfieldAthina Anastasaki
Mar 23, 2021·Accounts of Chemical Research·Grzegorz SzczepaniakKrzysztof Matyjaszewski
May 14, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Quentin Tévenot, Seiichi Kawahara
Jun 15, 2021·Chemical Science·Grzegorz SzczepaniakKrzysztof Matyjaszewski
Mar 19, 2019·Biomacromolecules·Adrian MorenoVirgil Percec
Apr 24, 2019·Biomacromolecules·Nabil BensabehVirgil Percec
Nov 30, 2021·JACS Au·Manon RollandAthina Anastasaki

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