Copper pumping ATPases: common concepts in bacteria and man

FEBS Letters
M SoliozR Krapf


Recently, four genes encoding putative copper pumping ATPases have been cloned from widely different sources: two genes from Enterococcus hirae that are involved in copper metabolism and two human genes that are defective in the copper-related Wilson and Menkes disease. The predicted gene products are P-type ATPases. They exhibit extensive sequence similarity and appear to be members of a new class of ATP driven copper pumps involved in the regulation of cellular copper.


Nov 30, 1992·Annals of the New York Academy of Sciences·A OdermattM Solioz
Jan 1, 1991·Annual Review of Physiology·J D HorisbergerB C Rossier
Oct 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·J S Cha, D A Cooksey
Feb 1, 1989·Trends in Biochemical Sciences·S SilverT K Misra
Jan 11, 1984·Nucleic Acids Research·J DevereuxO Smithies
Nov 30, 1993·Biochemical and Biophysical Research Communications·Y YamaguchiJ D Gitlin
Jan 1, 1993·Nature Genetics·J F MercerD Siemieniak


Oct 31, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M L SchilskyM J Czaja
May 6, 1996·Biochimica Et Biophysica Acta·J V MøllerM le Maire
Jan 23, 2002·Journal of Inorganic Biochemistry·Jason D CzachorJames Koropatnick
Jul 1, 1996·Journal of Hepatology·M DijkstraR J Vonk
Feb 6, 1998·The International Journal of Biochemistry & Cell Biology·R Nath
Jul 16, 2003·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Pamela Chavez-CrookerGregory A Ahearn
Mar 16, 2013·Chemical Reviews·Sonja EckhardtKatharina M Fromm
Dec 17, 2008·Nature Reviews. Microbiology·Kevin J Waldron, Nigel J Robinson
Apr 25, 2007·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Bonnie Ransom SternTom Starr
Dec 24, 1997·Annals of the New York Academy of Sciences·S LutsenkoJ H Kaplan
Mar 10, 2004·Applied and Environmental Microbiology·In Seop ChangLee R Krumholz
Aug 12, 2000·Journal of Bacteriology·P J Riggle, C A Kumamoto
Jan 1, 1996·Annual Review of Microbiology·S Silver, L T Phung
Aug 15, 2000·Annual Review of Nutrition·E D Harris
Jan 11, 2013·Oxidative Medicine and Cellular Longevity·Wayne Briner
Mar 10, 2001·Biochemical and Biophysical Research Communications·I VoskoboinikJ Camakaris
Nov 4, 2008·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Mathias LübbenM Solioz
Dec 19, 2013·The Journal of Membrane Biology·Sevdegul KaradasHalit Demir
Dec 21, 2004·Critical Reviews in Oncology/hematology·Roohangiz Safaei, Stephen B Howell
Dec 14, 2005·Journal of Molecular Biology·Carmen KulajtaHans-Georg Koch
Jun 28, 2003·FEMS Microbiology Reviews·M Solioz, Jivko V Stoyanov
Sep 1, 1996·Osteoarthritis and Cartilage·S S GlassonP A Jimenez
Jun 1, 1997·American Journal of Human Genetics·M S NanjiD W Cox
Jan 9, 2016·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Mehmet KabaHalit Demir
Jan 8, 2008·Journal of Inorganic Biochemistry·Kristina O PazehoskiCharles T Dameron
Sep 26, 2001·Nutrition Reviews·E D Harris
Apr 21, 1995·The Journal of Biological Chemistry·M Solioz, A Odermatt
Jul 8, 1999·The Journal of Nutrition·M M PeñaD J Thiele

Related Concepts

DNA-dependent ATPase
Hepatic Form of Wilson Disease
Menkes Kinky Hair Syndrome
Protein Folding, Globular

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

The Tendon Seed Network

Tendons are rich in the extracellular matrix and are abundant throughout the body providing essential roles including structure and mobility. The transcriptome of tendons is being compiled to understand the micro-anatomical functioning of tendons. Discover the latest research pertaining to the Tendon Seed Network here.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.


Incretins are metabolic hormones that stimulate a decrease in glucose levels in the blood and they have been implicated in glycemic regulation in the remission phase of type 1 diabetes. Here is the latest research.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Long COVID-19

“Long Covid-19” describes illness in patients who are reporting long-lasting effects of the SARS-CoV-19 infection, often long after they have recovered from acute Covid-19. Ongoing health issues often reported include low exercise tolerance and breathing difficulties, chronic tiredness, and mental health problems such as post-traumatic stress disorder and depression. This feed follows the latest research into Long Covid.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.