PMID: 7580857Jan 1, 1995Paper

Coproporphyrinogen III oxidase from barley and tobacco--sequence analysis and initial expression studies

Planta
E KruseB Grimm

Abstract

Coproporphyrinogen III oxidase (coprogen oxidase; EC 1.3.3.3) is part of the pathway from 5-amino-levulinate to protoporphyrin IX which is common in all organisms and catalyses oxidative decarboxylation at two tetrapyrrole side chains. We cloned and sequenced full-length cDNAs encoding coprogen oxidase from barley (Hordeum vulgare L.) and tobacco (Nicotiana tabacum L.). They code for precursor peptides of 43.6 kDa and 44.9 kDa, respectively. Import into pea plastids resulted in a processed tobacco protein of approx. 39 kDa, which accumulated in the stroma fraction. Induction of synthesis of recombinant putative tobacco mature coprogen oxidase consisting of 338 amino-acid residues in Escherichia coli at 20 degrees C result in a catalytically active protein of approx. 39 kDa, while induction of its formation at 37 degrees C immediately terminated bacterial growth, possibly due to toxic effects on the metabolic balance of tetrapyrrole biosynthesis. The plant coprogen oxidase gene was expressed to different extents in all tissues investigated. This is most likely due to the differing requirements for tetrapyrroles in different organs. The steady-state level of mRNA did not significantly differ in etiolated and greening barley leave...Continue Reading

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Citations

Oct 26, 2005·Plant Molecular Biology·Suchi SoodBaishnab C Tripathy
Apr 15, 1996·European Journal of Biochemistry·S Reinbothe, C Reinbothe
May 15, 1997·European Journal of Biochemistry·J M Roper, A G Smith
May 28, 2005·Canadian Journal of Microbiology·Moisés BlancoM Esperanza Cerdán
Feb 4, 2012·The Arabidopsis Book·Ryouichi TanakaTatsuru Masuda
Aug 5, 1997·Proceedings of the National Academy of Sciences of the United States of America·I LermontovaB Grimm
Sep 8, 2010·Journal of Hazardous Materials·Alieu Mohamed BahFeibo Wu
Feb 8, 2006·The Plant Journal : for Cell and Molecular Biology·Pascale WilliamsCarol Rivin
Mar 11, 2015·Plant Biotechnology Journal·Dilrukshi S K NagahatennaRyan Whitford
Oct 18, 2012·Plant Signaling & Behavior·Baishnab Charan Tripathy, Ralf Oelmüller
Sep 17, 2003·The Journal of Biological Chemistry·Daniela BreckauDieter Jahn
Aug 8, 2001·The Plant Journal : for Cell and Molecular Biology·A IshikawaT Asahi
Feb 10, 2016·PloS One·Fean Davisunjaya SarianMarc Jos Elise Cornelis van der Maarel
Dec 26, 2001·The Journal of Biological Chemistry·Suzanne P ClearyColin Robinson

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