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Copy number networks to guide combinatorial therapy for cancer and other disorders

bioRxiv

Jun 5, 2014

Andy Lin, Desmond James Smith

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Abstract

The dwindling drug pipeline is driving increased interest in the use of genome datasets to inform drug treatment. In particular, networks based on transcript data and protein-protein interactions have been used to design therapies that employ drug combinations. But there has been less f...read more

Mentioned in this Paper

Radiation Hybrids
Drug Combinations
Atherosclerosis
Pharmacotherapy
DNA, Complementary
Genome
Oncogenes
EGFR gene
Genes
Cell Survival
4
1
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  • Copy number networks to guide combinatorial therapy for cancer and other disorders

    bioRxiv

    Jun 5, 2014

    Andy Lin, Desmond James Smith

    PMID: 990005942

    DOI: 10.1101/005942

    Abstract

    The dwindling drug pipeline is driving increased interest in the use of genome datasets to inform drug treatment. In particular, networks based on transcript data and protein-protein interactions have been used to design therapies that employ drug combinations. But there has been less f...read more

    Mentioned in this Paper

    Radiation Hybrids
    Drug Combinations
    Atherosclerosis
    Pharmacotherapy
    DNA, Complementary
    4
    1

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