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Copy number variation and evolution in humans and chimpanzees

Genome Research

Nov 1, 2008

George H. PerryRichard Redon

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Abstract

Copy number variants (CNVs) underlie many aspects of human phenotypic diversity and provide the raw material for gene duplication and gene family expansion. However, our understanding of their evolutionary significance remains limited. We performed comparative genomic hybridization on a...read more

Mentioned in this Paper

Cell Differentiation Process
Pan troglodytes
Chromosomes, Human
Biological Evolution
Gene Duplication
Genome
Genome, Human
Genetic Polymorphism
Variation (Genetics)
Pan Genus
1
249
Paper Details
References
    • References64
    • Citations111
    • References64
    • Citations111
  • Copy number variation and evolution in humans and chimpanzees

    Genome Research

    Nov 1, 2008

    George H. PerryRichard Redon

    PMID: 18775914

    DOI: 10.1101/gr.082016.108

    Abstract

    Copy number variants (CNVs) underlie many aspects of human phenotypic diversity and provide the raw material for gene duplication and gene family expansion. However, our understanding of their evolutionary significance remains limited. We performed comparative genomic hybridization on a...read more

    Mentioned in this Paper

    Cell Differentiation Process
    Pan troglodytes
    Chromosomes, Human
    Biological Evolution
    Gene Duplication
    1
    249

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    Paper Details
    References
    • References64
    • Citations111
    • References64
    • Citations111
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