Core Outcome Measures for Research in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation for Acute Respiratory or Cardiac Failure: An International, Multidisciplinary, Modified Delphi Consensus Study

Critical Care Medicine
Carol HodgsonInternational ECMO Network

Abstract

Research evaluating outcomes in critically ill patients with acute respiratory and cardiac failure supported with extracorporeal membrane oxygenation has increased significantly. The objective was to identify a core set of outcomes that are essential to include in all clinical research evaluating the use of either venoarterial or venovenous extracorporeal membrane oxygenation in critically ill patients, particularly regarding safety and adverse events. A three-round modified Delphi process. Patients, caregivers, multidisciplinary clinicians, researchers, industry partners, and research funders were included. Participants represented key extracorporeal membrane oxygenation organizations, including the Extracorporeal Life Support Organization, the International Extracorporeal Membrane Oxygenation Network, clinicians from high volume extracorporeal membrane oxygenation centers, and extracorporeal membrane oxygenation researchers or former extracorporeal membrane oxygenation patients from five continents. We used recommended standards for the development of a core outcome set. Outcome measures identified from systematic reviews of the literature and from qualitative studies of survivors were mapped to the domains identified by the ...Continue Reading

References

Apr 26, 2008·BMJ : British Medical Journal·Gordon H GuyattUNKNOWN GRADE Working Group
May 5, 2010·International Journal of Epidemiology·Simon ThompsonUNKNOWN Emerging Risk Factors Collaboration
Nov 18, 2011·The New England Journal of Medicine·Daniel Brodie, Matthew Bacchetta
Aug 8, 2012·Trials·Paula R WilliamsonPeter Tugwell
Apr 19, 2013·Critical Care : the Official Journal of the Critical Care Forum·Cecile AubronVince Pellegrino
Mar 4, 2014·Journal of Clinical Epidemiology·Maarten BoersPeter Tugwell
Aug 12, 2015·Current Opinion in Critical Care·Bronagh BlackwoodLouise Rose
Feb 27, 2016·Heart & Lung : the Journal of Critical Care·Ralph TrammCarol Hodgson
Mar 5, 2016·Intensive Care Medicine·Christian KaragiannidisWolfram Windisch
Aug 30, 2016·Journal of Clinical Nursing·Ralph TrammCarol Hodgson
Oct 19, 2016·PLoS Medicine·Jamie J KirkhamPaula R Williamson
May 26, 2017·American Journal of Respiratory and Critical Care Medicine·Dale M NeedhamAlison E Turnbull
Jul 3, 2017·American Journal of Critical Care : an Official Publication, American Association of Critical-Care Nurses·Ralph TrammCarol Hodgson
Jul 7, 2017·Trials·Paula R WilliamsonBridget Young
Nov 3, 2017·PloS One·Carina BenstoemAndreas Goetzenich
Nov 18, 2017·PLoS Medicine·Jamie J KirkhamPaula R Williamson
Jan 23, 2018·Chest·Daniel BrodieUNKNOWN International ECMO Network (ECMONet)
Feb 17, 2018·Intensive Care Medicine·Darryl AbramsUNKNOWN International ECMO Network (ECMONet) and The Extracorporeal Life Support Organization (ELSO)
Mar 14, 2018·Annals of Family Medicine·Susan M SmithMartin Fortin
Mar 30, 2019·Current Opinion in Critical Care·Kirstie L HaywoodGavin D Perkins

❮ Previous
Next ❯

Citations

Nov 27, 2019·Intensive Care Medicine·Darryl AbramsDaniel Brodie
Oct 15, 2019·Critical Care Medicine·Martin Max
Aug 11, 2020·Current Opinion in Critical Care·Victor D DinglasDale M Needham
Nov 17, 2020·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Joseph E TonnaPeta M A Alexander
May 20, 2021·Nursing in Critical Care·Louise RoseUNKNOWN Del-COrS team
Sep 4, 2021·Australian Critical Care : Official Journal of the Confederation of Australian Critical Care Nurses·Krista A KnudsonLois S Sadler
Jul 20, 2020·Lancet·Alain CombesDaniel Brodie
Jun 3, 2021·Critical Care Medicine·Carol L HodgsonUNKNOWN SCOPE Study Investigators on behalf of the International ECMO Network

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.