Core outcome sets and systematic reviews

Systematic Reviews
Mike Clarke, Paula Williamson

Abstract

Systematic reviews seek to bring together research evidence to answer the question for the review. The reviewers usually wish to compare, contrast and, if appropriate, combine the findings of the existing research studies. However, these intentions are often thwarted by inconsistencies in the outcomes that were measured and reported in the individual studies. This, in turn, makes it difficult for readers of the review to use it to make informed decisions and choices about health and social care. One solution is for trials in a particular topic area to measure and report a standardised set of outcomes, which would then be used in the review. Core outcome sets are a means of doing this, providing an agreed standardised collection of outcomes for measuring and reporting for a specific area of health. In this commentary, we argue for greater involvement of systematic reviewers in the development and implementation of core outcome sets. This might help with, for example, the selection of outcomes to include in the Summary of findings tables that provide users of the review with the key quantitative findings. Consideration of core outcome sets when reviewers register their topics with Cochrane Review Groups or in PROSPERO would also ...Continue Reading

References

Jan 1, 1981·Cancer·A B MillerA Winkler
May 4, 2010·Journal of Clinical Epidemiology·Sarah E RosenbaumAndrew D Oxman
Jan 17, 2013·Systematic Reviews·Alison BoothLesley Stewart
Oct 10, 2013·Trials·Jamie J KirkhamPaula R Williamson
Dec 12, 2013·Journal of Evidence-based Medicine·Clive E AdamsAnnabelle Wolff
Jan 15, 2014·Lancet·Paul GlasziouElizabeth Wager
Jul 12, 2014·Trials·Elizabeth GargonMike Clarke
Dec 3, 2014·Journal of Clinical Epidemiology·Valerie SmithElizabeth Gargon
May 15, 2015·Trials·Mike Clarke, Paula Williamson
Aug 25, 2015·Trials·Jamie J KirkhamUNKNOWN COS-STAR Group

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Citations

Apr 14, 2016·Journal of Dentistry·Padhraig S FlemingNikolaos Pandis
Sep 25, 2016·Human Reproduction·Jack WilkinsonAndy Vail
Oct 19, 2016·PLoS Medicine·Jamie J KirkhamPaula R Williamson
Feb 2, 2017·Journal of Clinical Epidemiology·Hayet AmeurAgnes Dechartres
May 10, 2017·Journal of Clinical Epidemiology·Jos VerbeekChristina Mischke
Apr 6, 2018·PloS One·Youri YordanovPhilippe Ravaud
Dec 19, 2017·The Clinical Journal of Pain·Svjetlana DosenovicLivia Puljak
Oct 27, 2016·Critical Care : the Official Journal of the Critical Care Forum·Mohamed D HashemMichelle N Eakin
Jul 7, 2017·Trials·Paula R WilliamsonBridget Young
Apr 11, 2018·BMJ Paediatrics Open·Sophie Kuizenga-WesselMerit Monique Tabbers
Feb 13, 2019·Trials·Jamie J KirkhamUNKNOWN COS-STAP Group
Jan 8, 2020·Interactive Journal of Medical Research·Alice HibbertDeborah Ann Hall
Oct 20, 2020·Hernia : the Journal of Hernias and Abdominal Wall Surgery·A Gram-HanssenJ Rosenberg
Oct 14, 2020·Critical Care Medicine·Ericka L FinkUNKNOWN Pediatric Outcomes STudies after PICU (POST-PICU) Investigators of the Pediatric Acute Lung Injury and Sepsis Investigators
Jan 22, 2021·American Journal of Public Health·Luke WolfendenSze Lin Yoong
Oct 14, 2020·The Journal of Infection·Kieran A WalshMichelle O'Neill
Jan 29, 2021·Annals of Global Health·Niki O'BrienKarolin R Krause
Mar 13, 2021·HRB Open Research·Karen Matvienko-SikarUNKNOWN MRC-NIHR TMRP Outcomes Working Group Core Outcome Set Theme
May 12, 2021·Journal of Clinical Epidemiology·Ian J SaldanhaPaula R Williamson
Jun 29, 2021·Frontiers in Aging Neuroscience·Jorge Piano SimoesEleni Genitsaridi
Jul 18, 2021·European Child & Adolescent Psychiatry·Karolin Rose KrauseMiranda Wolpert
Jul 5, 2021·BJOG : an International Journal of Obstetrics and Gynaecology·O KgosidialwaUNKNOWN INSPIRED Research Group

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Software Mentioned

COSMIN
PROSPERO
COMET

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