Core-Shell Magnetic Mesoporous Silica Microspheres with Large Mesopores for Enzyme Immobilization in Biocatalysis

ACS Applied Materials & Interfaces
Yu ZhangYonghui Deng

Abstract

Magnetic mesoporous silica microspheres with core-shell structure and large pores are highly desired in macromolecules delivery and biocatalysis, biospeparation, and adsorption. In this work, a controllable solvent evaporation induced solution-phase interface co-assembly approach was developed to synthesize core-shell structural magnetic mesoporous silica microspheres with ultralarge mesopore size (denoted as LP-MMS). The synthesis was achieved by employing large-molecular-weight amphiphilic block copolymers poly(ethylene oxide)- block-poly(methyl methacrylate) (PEO- b-PMMA) and small surfactant cetyltrimethylammonium bromide as co-templates, which can co-assemble with silica source in tetrahydrofuran/water solutions. The obtained LP-MMS microspheres possess uniform rasberry-like morphology with a diameter of 600 nm, large primary spherical mesopores (ca. 36 nm), large specific surface area (348 m2/g), high specific pore volume (0.59 cm3/g), and fast magnetic responsivity with high magnetization (15.9 emu/g). The mesopore morphology can be transformed from spherical to cylindrical through introducing a shearing force during the interfacial co-assembly in the synthesis system. The designed LP-MMS microspheres turn out to be good...Continue Reading

References

Jun 24, 2000·Nature·A Pandey, M Mann
Dec 19, 2002·Molecular & Cellular Proteomics : MCP·N Leigh Anderson, Norman G Anderson
Jun 23, 2005·Journal of the American Chemical Society·Wenru ZhaoJianlin Shi
Apr 15, 2006·Science·Bruno Domon, Ruedi Aebersold
Dec 29, 2006·Small·Yahong ZhangBaohong Liu
Feb 11, 1983·Science·A M Klibanov
Feb 20, 2008·Accounts of Chemical Research·Young-Wook JunJinwoo Cheon
May 29, 2010·Journal of the American Chemical Society·Yonghui DengDongyuan Zhao
Jun 8, 2013·Chemical Communications : Chem Comm·Madhappan Santha MoorthyChang-Sik Ha
Oct 31, 2015·Advanced Materials·Victor MalgrasYusuke Yamauchi
Dec 3, 2015·Chemistry : a European Journal·Yi-Syuan LuShiao-Wei Kuo
Mar 10, 2017·Journal of the American Chemical Society·Qin YueDongyuan Zhao

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Citations

Oct 22, 2019·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Antony RajendranWen-Ying Li
Apr 30, 2021·Journal of the American Chemical Society·Andres F Chaparro SosaJoel L Kaar
Jun 11, 2021·Journal of Agricultural and Food Chemistry·Xiang-Ping KongJuan Wang

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