Core, social and moral disgust are bounded: A review on behavioral and neural bases of repugnance in clinical disorders

Neuroscience and Biobehavioral Reviews
Carmelo M VicarioAlessio Avenanti

Abstract

Disgust is a multifaceted experience that might affect several aspects of life. Here, we reviewed research on neurological and psychiatric disorders that are characterized by abnormal disgust processing to test the hypothesis of a shared neurocognitive architecture in the representation of three disgust domains: i) personal experience of 'core disgust'; ii) social disgust, i.e., sensitivity to others' expressions of disgust; iii) moral disgust, i.e., sensitivity to ethical violations. Our review provides some support to the shared neurocognitive hypothesis and suggests that the insula might be the "hub" structure linking the three domains of disgust sensitivity, while other brain regions may subserve specific facets of the multidimensional experience. Our review also suggests a role of serotonin core and moral disgust, supporting "neo-sentimentalist" theories of morality, which posit a causal role of affect in moral judgment.

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Citations

May 30, 2017·Acta Psychologica·Carmelo M VicarioRobert D Rafal
Apr 17, 2019·Journal of Health Psychology·Carmelo M VicarioKim Felmingham
Apr 18, 2019·Social Cognitive and Affective Neuroscience·Mamdooh AfdileMikko Sams
Mar 9, 2018·Royal Society Open Science·Marco Tullio LiuzzaJonas K Olofsson
Apr 30, 2020·Social Cognitive and Affective Neuroscience·Carmelo M VicarioAlessio Avenanti
Mar 21, 2019·Frontiers in Psychology·Marco Tullio LiuzzaTorun Lindholm
Sep 16, 2020·Scientific Reports·Nicolas LegrandPierre Gagnepain
Nov 8, 2017·Brain : a Journal of Neurology·Hernando Santamaría-GarcíaAgustín Ibáñez
Apr 25, 2018·Frontiers in Psychiatry·Carmelo M Vicario, Kim Felmingham
Jan 1, 2018·Substance Abuse : Official Publication of the Association for Medical Education and Research in Substance Abuse·Deborah S Finnell
Feb 23, 2020·PloS One·Sara BorgomaneriAlessio Avenanti
Feb 18, 2020·Frontiers in Psychology·Patrick A StewartCarl Senior
Jul 28, 2020·Frontiers in Psychology·Olga HoltmannThomas Straube
Sep 26, 2020·Frontiers in Psychology·Carmelo Mario VicarioGabriella Martino
Oct 13, 2017·Human Brain Mapping·Jesus PujolAssumpta Caixàs
May 17, 2018·Eating and Weight Disorders : EWD·Rami Bou KhalilHayat Azouri
Sep 15, 2018·Frontiers in Behavioral Neuroscience·Megan OatenTrevor I Case
Nov 30, 2019·Frontiers in Psychology·Gabriella MartinoCarmelo Mario Vicario
Feb 16, 2021·Behavioral Ecology and Sociobiology·Peter Kramer, Paola Bressan
May 1, 2021·International Journal of Environmental Research and Public Health·Chiara LuciforaCarmelo Mario Vicario

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