Corneal backward scattering and higher-order aberrations in children with vernal keratoconjunctivitis and normal topography

Acta Ophthalmologica
Tommy C Y ChanVishal Jhanji

Abstract

To investigate the corneal backward scattering and higher-order aberrations (HOAs) in children with vernal keratoconjunctivitis (VKC) and normal topography. Thirty-six eyes of 22 patients with VKC and 54 eyes of 34 normal subjects were included. All participants had clear cornea, absence of dry eyes and a normal corneal tomography. Scheimpflug imaging was used to measure corneal backward scattering in zones centred on the corneal apex (central 2-mm zone and paracentral 2- to 6-mm zone), and HOAs were compared between VKC and normal control. The mean age of participants was 12.0 ± 4.1 years in VKC group and 11.2 ± 4.1 years in control group (p = 0.339). There was no significant intergroup difference in mean keratometry, astigmatism and apex pachymetry (p ≥ 0.076). Total corneal backscatter was higher in the VKC group compared to the control group (p ≤ 0.012). Anterior and posterior cornea displayed a higher level of backward scattering in the VKC group (p < 0.001 for anterior; p ≤ 0.048 for posterior). Patients with VKC exhibited higher total HOAs and coma (p ≤ 0.036). There were significant correlations between total anterior HOAs and backward scattering measured at the central (r = 0.500; p = 0.032) and paracentral zones (r = ...Continue Reading

References

Nov 1, 1989·Ophthalmology·J A CameronI A Badr
Oct 1, 1989·Archives of Ophthalmology·S SawaguchiJ E Gilboy
Oct 1, 1983·American Journal of Ophthalmology·A Gormaz, C Eggers
Apr 8, 2004·Eye·S BoniniA Lambiase
Nov 24, 2005·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Clare O'Donnell, James S Wolffsohn
Jan 24, 2006·Progress in Retinal and Eye Research·Naoki KumagaiTeruo Nishida
May 18, 2006·Acta Ophthalmologica Scandinavica·Andrea LeonardiAntonio G Secchi
Dec 16, 2006·American Journal of Ophthalmology·Jackson BarretoSamir Jacob Bechara
Jun 27, 2007·Investigative Ophthalmology & Visual Science·Ryo KosakiYasuo Tano
Nov 26, 2008·Investigative Ophthalmology & Visual Science·Tomoya NakagawaYasuo Tano
Jun 11, 2009·Cornea·Charles W McMonnies
Apr 13, 2010·Ophthalmology·Marta SacchettiStefano Bonini
Oct 23, 2010·The Ocular Surface·Robert Montés-MicóDavid Madrid-Costa
May 17, 2011·Annual Review of Biomedical Engineering·Jeffrey W RubertiCynthia J Roberts
Dec 3, 2011·Ophthalmology·Ahmad Muneer OtriHarminder S Dua
Dec 20, 2011·Ophthalmology·Andrea LeonardiIva Fregona
May 18, 2012·Ophthalmology·Alexandre DenoyerChristophe Baudouin
Oct 1, 2013·Seminars in Ophthalmology·Marcella NebbiosoMarzia Duse
Nov 19, 2013·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Anna Maria ZicariMarzia Duse
Dec 12, 2013·Investigative Ophthalmology & Visual Science·Sorcha Ní DhubhghaillMarie-José Tassignon
Sep 23, 2014·Investigative Ophthalmology & Visual Science·Shizuka KohKohji Nishida
Oct 7, 2014·Cornea·Bernardo LopesRenato Ambrósio
Oct 27, 2015·Medicine·Edoardo VillaniPaolo Nucci

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.