Corneal Biomechanical Changes and Tissue Remodeling After SMILE and LASIK

Investigative Ophthalmology & Visual Science
Rohit ShettyAbhijit Sinha Roy

Abstract

To evaluate transient corneal tissue healing and biomechanical changes between laser in situ keratomileusis (LASIK) and small incision lenticule extraction (SMILE) eyes. In each patient, one eye underwent LASIK and the other underwent SMILE. Optical coherence tomography (OCT) and dynamic Scheimpflug imaging (Corvis-ST) was used to assess tissue healing and biomechanics, respectively. Analyses of OCT scans yielded corneal speckle distribution (CSD) and Bowman's roughness index (BRI). Waveform analyses of deformation amplitude yielded corneal stiffness. Further, corneal force versus corneal deformation data helped compare the two procedures. BRI increased and then decreased transiently after both treatments (P < 0.05). However, SMILE eyes had BRI similar to that of their preoperative state compared to LASIK eyes at 6-month follow-up. CSD indicated a marked increase in the number of bright pixels and a decrease in the number of dark pixels after SMILE (1-month follow-up) and LASIK eyes (3-month follow-up), respectively. CSD returned to near preoperative state thereafter, respectively. Corneal stiffness change from preoperative state was similar between LASIK and SMILE eyes. However, deformation at discrete values of corneal force ...Continue Reading

Citations

Nov 7, 2018·Investigative Ophthalmology & Visual Science·Mathew FrancisAbhijit Sinha Roy
May 7, 2019·Journal of Refractive Surgery·Pooja KhamarAbhijit Sinha Roy
Jul 25, 2019·Investigative Ophthalmology & Visual Science·Alejandra ConsejoD Robert Iskander
Feb 15, 2019·Biomedical Engineering Online·Magdalena Jędzierowska, Robert Koprowski
Aug 12, 2020·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Cecilia ChaoFiona Stapleton
Feb 6, 2020·Optometry and Vision Science : Official Publication of the American Academy of Optometry·D Robert IskanderPatrycja Krzyżanowska-Berkowska
Aug 25, 2020·Translational Vision Science & Technology·Alejandra ConsejoD Robert Iskander
Aug 22, 2020·Translational Vision Science & Technology·Gongpu LanMichael D Twa
May 28, 2020·Investigative Ophthalmology & Visual Science·Lingjia LiuYan Wang
May 31, 2019·Translational Vision Science & Technology·Aris KonstantopoulosJodhbir S Mehta
Jul 25, 2020·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Alejandra ConsejoStephen J Vincent
May 14, 2020·Journal of Cataract and Refractive Surgery·Markus V OlsenXiangjun Chen
May 27, 2020·Current Opinion in Ophthalmology·Evan K DackowskiRoy S Chuck
Jan 5, 2021·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Gongpu LanMichael D Twa
Mar 11, 2021·Journal of Ophthalmology·Sang Beom HanJodhbir S Mehta
Apr 7, 2021·Seminars in Ophthalmology·Grace Huang, Samir Melki
Dec 17, 2021·Journal of Refractive Surgery·Bogdan SpiruWalter Sekundo

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