Corneal cross-linking for Acanthamoeba keratitis in an orthokeratology patient after swimming in contaminated water

Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association
Ángeles Arance-GilJosé Manuel González-Méijome

Abstract

To report a case of Acanthamoeba keratitis diagnosed using confocal microscopy in a patient corrected by orthokeratology and treated with corneal crosslinking (CXL) after failure to respond to medical treatment. After diagnosis, the patient was treated with several medications until CXL was applied during one 30-min session using ultraviolet A radiation and application of riboflavin. The clinical signs of the disease observed using slit-lamp biomicroscopy and confocal microscopy were evaluated and the visual acuity was measured during the course of the infection and treatment over a period of 30 months including 12 months of medical treatment, 9 months after cross-linking and amniotic membrane transplant and 9 months after penetrating keratoplasty and cataract extraction. In this case, confocal microscopy facilitated early diagnosis of an Acanthamoeba infection even if other signs and symptoms might be confounding. CXL was more effective than aggressive medication against the microorganism. After CXL, the symptoms and the corneal appearance improved significantly but the ulcer did not heal completely. After amniotic membrane transplantation, the patient underwent penetrating keratoplasty (PK) with no rejection, and the visual f...Continue Reading

References

Oct 15, 1989·American Journal of Ophthalmology·L FickerP Wright
Nov 4, 1989·South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde·R MaskeA J Lastovica
Feb 1, 1974·The British Journal of Surgery·A PrakashP N Prandit
Apr 26, 2002·The British Journal of Ophthalmology·C F RadfordJ K G Dart
Apr 30, 2003·American Journal of Ophthalmology·Gregor WollensakTheo Seiler
Dec 24, 2003·Investigative Ophthalmology & Visual Science·Simon KilvingtonMelville Matheson
Feb 16, 2005·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Jennifer ChooPatrick Caroline
Sep 16, 2005·Eye & Contact Lens·Kathleen Watt, Helen A Swarbrick
Dec 8, 2005·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·R N Borazjani, S Kilvington
Aug 11, 2006·Current Opinion in Ophthalmology·Kristin M Hammersmith
Aug 2, 2007·Cornea·Mozhgan Rezaei KanaviSeyedali Mirdehghanm
Dec 6, 2007·Eye & Contact Lens·Kathleen G Watt, Helen A Swarbrick
May 30, 2008·Acta Ophthalmologica·Hsin-Chiung LinSamuel Chao-Ming Huang
Jun 13, 2008·Acta Ophthalmologica·Gregor Wollensak, Elena Iomdina
Sep 23, 2008·Ophthalmology·Woodford S Van MeterUNKNOWN American Academy of Ophthalmology
Jan 22, 2009·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Jennifer D ChooMark D P Willcox
Mar 24, 2009·Journal of Cataract and Refractive Surgery·Paolo RamaAlessandra Spinelli
Nov 19, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Karim MakdoumiSven Crafoord
Mar 26, 2010·Investigative Ophthalmology & Visual Science·Arnaud SauerTristan Bourcier
Nov 13, 1915·British Medical Journal·G C Low
Aug 31, 2010·Ophthalmology·Pravin K VaddavalliRavi Thomas
Aug 31, 2010·Current Opinion in Infectious Diseases·Govinda S Visvesvara
Sep 3, 2010·The British Journal of Ophthalmology·S G ShahM Lakshmipathy
Nov 3, 2010·American Journal of Ophthalmology·Elmer Y Tu, Charlotte E Joslin

❮ Previous
Next ❯

Citations

May 21, 2015·Acta Ophthalmologica·Tommy C Y ChanRaymond L M Wong
Oct 29, 2015·Cornea·Lamprini PapaioannouMiltiadis Papathanassiou
Mar 15, 2015·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Xianmin FengShijie Lv
Apr 30, 2015·Journal of Ophthalmology·Xiao ZhangGuo-Ying Mu
May 26, 2015·Journal of Ophthalmic & Vision Research·David TabibianFarhad Hafezi
Jan 17, 2017·Journal of Pediatric Ophthalmology and Strabismus·Xintong LiCheng Zhang
Jan 15, 2018·Parasitology Research·Denise Leal Dos SantosMarilise Brittes Rott
Aug 21, 2018·The Open Ophthalmology Journal·Li Lim, Elizabeth Wen Ling Lim
Apr 17, 2018·BMJ Open Ophthalmology·Yen C HsiaJennifer Rose-Nussbaumer
Jan 9, 2018·Ocular Immunology and Inflammation·Chiara BonzanoCarlo Enrico Traverso
May 24, 2017·Infection·Ka Wai KamAlvin L Young
Oct 24, 2020·Journal of Water and Health·Lea D BallaresGiovanni D Milanez
Oct 30, 2020·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Ana Gomes de Lacerda, Madalena Lira
Dec 25, 2019·Journal français d'ophtalmologie·A-S GauthierB Delbosc
Mar 28, 2021·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Kelsy R SteeleAaron B Zimmerman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Refractive Surgery
Salvador Garcia-DelpechDavid Salom
American Journal of Ophthalmology
Sun XuguangJin Xiuying
American Journal of Ophthalmology
Juha M Holopainen, Kari Krootila
© 2021 Meta ULC. All rights reserved