Corneal endothelial cell density and morphology in normal Iranian eyes

BMC Ophthalmology
Mohammad Nasser HashemianMohammad Reza Mansouri

Abstract

We describe corneal endothelial cell density and morphology in normal Iranian eyes and compare endothelial cell characteristics in the Iranian population with data available in the literature for American and Indian populations. Specular microscopy was performed in 525 eyes of normal Iranian people aged 20 to 85 years old. The studied parameters including mean endothelial cell density (MCD), mean cell area (MCA) and coefficient of variation (CV) in cell area were analyzed in all of the 525 eyes. MCD was 1961 +/- 457 cell/mm2 and MCA was 537.0 +/- 137.4 microm2. There was no statistically significant difference in MCD, MCA and CV between genders (Student t-test, P = 0.85, P = 0.97 and P = 0.15 respectively). There was a statistically significant decrease in MCD with age (P < 0.001, r = -0.64). The rate of cell loss was 0.6% per year. There was also a statistically significant increase in MCA (P < 0.001,r = 0.56) and CV (P < 0.001, r = 0.30) from 20 to 85 years of age. The first normative data for the endothelium of Iranian eyes seems to confirm that there are no differences in MCD, MCA and CV between genders. Nevertheless, the values obtained in Iranian eyes seem to be different to those reported by the literature in Indian and ...Continue Reading

References

Nov 1, 1978·Archives of Ophthalmology·A LauleC Hanna
Jun 1, 1976·Experimental Eye Research·R A LaingH M Leibowitz
Jan 1, 1985·Archives of Ophthalmology·M MatsudaH F Edelhauser
Jun 1, 1985·Current Eye Research·R W YeeH F Edelhauser
Oct 1, 1985·Archives of Ophthalmology·H ChengM J Noble
Jun 1, 1982·Ophthalmology·S Mishima
Sep 1, 1980·Ophthalmology·K J Hoffer, M C Kraff
Jun 1, 1994·Ophthalmology·W M BourneD O Hodge
Jul 1, 1995·Journal of Cataract and Refractive Surgery·M LandeszG Van Rij
Jun 1, 2000·Journal of Cataract and Refractive Surgery·T WalkowS Klebe
Jun 30, 2000·The British Journal of Ophthalmology·A MüllerL Wright
Apr 13, 2004·Cornea·Ma Dominga B PadillaClarissa S A Gonzales
Jun 7, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Henry Ho-Lung Chan

❮ Previous
Next ❯

Citations

Mar 1, 2008·Clinical Ophthalmology·Narumon SopapornamornSuthee Panichkul
Aug 29, 2012·Clinical Ophthalmology·Saulius GalgauskasRimvydas-Stanislovas Asoklis
Apr 1, 2014·Journal of Ophthalmology·Ceyhun ArıcıFunda Dikkaya
Jul 31, 2014·Clinical Interventions in Aging·Saulius GalgauskasJanina Tutkuvienė
May 25, 2011·Biomaterials·Steven A KoopmansTheo G van Kooten
Apr 3, 2015·Acta Ophthalmologica·Pekka RuusuvaaraKirsi Setälä
Jan 11, 2014·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Michael J Doughty
Aug 7, 2012·Acta Ophthalmologica·Stephan J LinkeOlaf J C Hellwinkel
May 24, 2011·PloS One·Carlos H WörnerNuria Garzón-Jiménez
Apr 5, 2017·Cell and Tissue Banking·Nigel H Brookes
Nov 26, 2013·Cell Transplantation·Gary S L PehJodhbir S Mehta
Mar 13, 2010·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Jose Manuel González-MéijomeManuel A Parafita
Mar 20, 2010·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Junko KoshimizuTatsuo Yamaguchi
Oct 8, 2019·Journal of Cataract and Refractive Surgery·Jae Hwan ChoiTae-Young Chung
Jun 1, 2017·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Qamar Ul IslamMohammad Asim Mehboob
Dec 23, 2016·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Rahmi Dumanİrfan Perente
Mar 29, 2019·Journal of Ophthalmology·Marwa Mahmoud AbdellahMohamed Gamal Elghobaier
Apr 30, 2020·BMC Ophthalmology·Napaporn Tananuvat, Natawan Khumchoo
Apr 2, 2021·Clinical Ophthalmology·Syed Bilal Hassan Zaidi, Wajid Ali Khan
Apr 24, 2021·BMC Ophthalmology·Joseph-Theodore K KelekeleJean-Claude Mwanza
Apr 30, 2021·Indian Journal of Ophthalmology·Rajan Sharma, Ashok Sharma
May 20, 2021·Clinical Ophthalmology·Iwan SoebijantoroMarsetyawan Soesatyo
Sep 29, 2007·Ophthalmology·Naoko KatoKazuo Tsubota

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.