PMID: 6536424Jan 1, 1984Paper

Corneal endothelial changes caused by ophthalmic drugs

Cornea
K SasamotoM Itoi

Abstract

Morphological changes were examined in the corneal endothelium of rabbits after administration of several drugs widely used in ophthalmology. After administration of epinephrine and dipivalyl epinephrine eye drops, swelling of corneal endothelial cells developed; however, these changes were reversible. No pathological changes were observed in the corneal endothelial layer following the administration of timolol, betamethasone, and gentamicin eye drops. Morphological changes were observed in the corneal endothelial layer after the subconjunctival injection of timolol, betamethasone, and gentamicin.

Citations

Jan 1, 1987·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·G S LiuG E Trope
Apr 27, 2002·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Pascal FurrerRobert Gurny
Apr 1, 1992·The British Journal of Ophthalmology·M Pande, F Ghanchi
Mar 15, 1992·American Journal of Ophthalmology·D SatterfieldA T Glover

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