PMID: 6536428Jan 1, 1984Paper

Corneal epithelial response of the primate eye to gas permeable corneal contact lenses: a preliminary report

Cornea
J P BergmansonL W Chu

Abstract

The comparative corneal epithelial effects of rigid gas permeable and soft contact lenses are reported in the present preliminary study using two bush baby monkeys (Galago senegalensis). Both types of lenses produced early cell death among the surface squamous cells while internally the epithelium and its nerve fibers remained normal. Sporadically small abnormal groups of cells involving two to three of the surface layers were observed in both the hard and soft lens wearing corneas. It was concluded that this represented superficial punctate keratitis (SPK). Small superficial intracellular epithelial cysts with membranous contents were infrequently noted in the gas permeable lens wearing cornea and it is suggested here that they were mild forms or precursors of those seen clinically in human corneas. Since the gas permeable lens met the corneal oxygen requirement it is postulated that the traumatic effect of the rigidity of the lens caused the cystic formation to occur. The relative hypoxia induced by the soft contact lens resulted in a mild superficial epithelial edema.

Citations

Jan 9, 2001·Optometry and Vision Science : Official Publication of the American Academy of Optometry·N Efron
Jan 5, 2008·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Keith W Ward
Dec 5, 2013·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Boris SeverinskyAbraham Solomon
Jan 1, 1989·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·T TervoA Tarkkanen
Dec 3, 2014·Progress in Retinal and Eye Research·A J BronF V Bright
Dec 11, 2002·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Nathan Efron

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