Corneal regeneration after femtosecond laser small-incision lenticule extraction: a prospective study

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Manli LiuQuan Liu

Abstract

To evaluate the morphologic changes of corneal after small incision lenticule extraction (SMILE) using the Heidelberg Retina Tomograph III (HRT III)/Rostock Cornea Module confocal microscope and three-dimensional optical coherence tomography (3D-OCT). Thirty eyes of 30 patients who underwent SMILE for the correction of myopia and myopic astigmatism in this study. Morphologic modifications of corneal architecture and the density of corneal subbasal nerve were evaluated prior to SMILE and 7 days, 1, 3, and 6 months after SMILE by in-vivo confocal microscopy (IVCM) and 3D-OCT. The corneal epithelium morphology showed no particular changes during the entire 6-month examination period. Subbasal nerve density recovered to preoperative levels within 3 months after SMILE (P > 0.05). On the interface layer, intense keratocyte activity was noted in all eyes after SMILE. The corneal fibrotic tissues on the interface layer diminished with time, but the persistence of brightly reflective particles still existed. No particular change between preoperative and postoperative corneal endothelium. The incision margin of SMILE had the appearance of a less clearly identified fibrotic scar with epithelial plug. IVCM and 3D-OCT analysis showed that t...Continue Reading

References

Oct 27, 2004·Investigative Ophthalmology & Visual Science·Martha P CalvilloWilliam M Bourne
Jun 13, 2006·American Journal of Ophthalmology·Seung Jae LeeHyung Keun Lee
Jun 27, 2006·Investigative Ophthalmology & Visual Science·Bertrand SonigoChristophe Baudouin
Dec 25, 2010·Journal of Cataract and Refractive Surgery·Rupal ShahSayantan Sengupta
Feb 11, 2012·Investigative Ophthalmology & Visual Science·Marcus AngJodhbir S Mehta
Jul 13, 2012·Investigative Ophthalmology & Visual Science·Fengju ZhangXuguang Sun
Jun 25, 2013·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Anders H VestergaardJesper Ø Hjortdal
Oct 12, 2013·American Journal of Ophthalmology·Kazutaka KamiyaHidenaga Kobashi
Feb 27, 2014·Investigative Ophthalmology & Visual Science·Karim Mohamed-NoriegaJodhbir S Mehta
Mar 22, 2014·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Walter SekundoIgor Solomatin
Sep 11, 2014·Journal of Refractive Surgery·Miguel A Teus, Montserrat Garcia-Gonzalez
Oct 2, 2014·Klinische Monatsblätter für Augenheilkunde·K S KunertM Blum

❮ Previous
Next ❯

Citations

Oct 11, 2016·Journal of Refractive Surgery·Manli LiuQuan Liu
Oct 29, 2018·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Tommy C Y ChanYan Wang
Mar 5, 2019·Vestnik oftalmologii·S E AvetisovZ V Surnina
Sep 10, 2020·Journal of Refractive Surgery·Norman RomitoNacim Bouheraoua
Jun 7, 2019·European Journal of Ophthalmology·Ke ZhengXingtao Zhou
Jul 25, 2017·Journal of Cataract and Refractive Surgery·Nikolaus LuftMartin Dirisamer
Jan 12, 2019·Neural Regeneration Research·Francisco BandeiraJodhbir Singh Mehta
Oct 1, 2017·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Yugui ZhouQuan Liu
Jul 9, 2021·Journal of Refractive Surgery·Stephen StewartJodhbir S Mehta

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.