Corneal thickness change induced by dozing while wearing hydrogel and silicone hydrogel lenses

Eye & Contact Lens
Hikaru HamanoSetsuko Kotani

Abstract

The physiologic effects on the cornea of dozing while wearing contact lenses were assessed by using central corneal swelling as an index in relation with lens oxygen transmissibility (Dk/t). Two hydrogel lens materials (nelfilcon A and etafilcon A) with a power of -0.50 diopters (D) and three silicone hydrogel lens materials (galyfilcon A, senofilcon A, and lotrafilcon A) with a power of -0.50 D were studied on 16 eyes of eight subjects with no previous experience of contact lens wear and no ocular disease. The subjects wore the lenses for seven continuous hours with their eyelids closed for 1 hour after the first 3 hours of lens wear to simulate a dozing condition. Corneal thickness was measured with a specular microscope with a built-in pachometer (Topcon SP-2000P). The same measurement was performed for the non-lens-wearing eyes as the control. Swelling rates immediately after dozing were 4.8%+/-1.4% for nelfilcon A, 5.2%+/-1.7% for etafilcon A, 2.8%+/-1.2% for galyfilcon A, 1.9%+/-0.8% for senofilcon A, and 1.5%+/-1.6% for lotrafilcon A. The swelling rates for the two hydrogel lenses were significantly higher (P<0.001) than that for the control (1.8%+/-1.5%), and the differences remained significant after 3 hours. Conversel...Continue Reading

References

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Citations

Jul 13, 2013·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Kathryn A DumbletonLyndon W Jones
Feb 5, 2015·Journal of Optometry·Amir M MoezziTrefford L Simpson
Mar 17, 2010·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Jessie CharmPauline Cho
Feb 27, 2020·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Anna Sulley, Kathy Dumbleton
Dec 21, 2020·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·M J Doughty
Mar 30, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Philip B MorganMark Willcox
May 19, 2021·Translational Vision Science & Technology·Russell ThomsonDeborah F Sweeney

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