Coronary and cerebral thrombosis in a young patient after mild COVID-19 illness: a case report

European Heart Journal. Case Reports
Lauren S RanardAmirali Masoumi

Abstract

COVID-19 has spread worldwide and has caused significant morbidity and mortality. Myocardial injury and thrombo-embolism are known complications for those with severe forms of disease. The incidence and risk factors for these complications for those patients who are asymptomatic or with mild forms of COVID-19 is unknown. In this report we describe the case of a 35-year-old man with no past cardiac history who presented with chest pain and a high-sensitivity troponin level of 386 ng/L in the context of an unspecified mild viral illness 1 month previously. Diagnostic evaluation revealed a new cardiomyopathy, left ventricular thrombus, and mid right coronary artery thrombosis. The coronary thrombosis was treated with thrombectomy. SARS-CoV-2 antibodies returned positive. He initially did well post-procedure; however, prior to discharge, he developed a second arterial thrombo-embolism event, a middle cerebral artery stroke. He was treated with thrombectomy and remains hospitalized. Recognition that mild COVID-19 can be complicated by subsequent cardiac injury and/or coagulopathy is important. As more people recover from this viral illness and return to normal activity levels, discussion among cardiac experts has begun regarding scr...Continue Reading

References

Feb 23, 2020·The Lancet Infectious Diseases·Ensheng DongLauren Gardner
Apr 24, 2020·Lancet·Zsuzsanna VargaHolger Moch
Apr 28, 2020·Blood·Jean M Connors, Jerrold H Levy
May 1, 2020·Thrombosis Research·Corrado LodigianiUNKNOWN Humanitas COVID-19 Task Force
May 7, 2020·European Heart Journal·Pablo Dominguez-ErquiciaAndrés Iñiguez-Romo
Jun 6, 2020·Circulation. Heart Failure·Lauren S RanardAmirali Masoumi

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Citations

Jan 13, 2021·BMJ Case Reports·Elin Hoffmann DahlBjørn Blomberg
Feb 15, 2021·Reviews in the Neurosciences·Giovanni FrisulloPaolo Calabresi
Apr 17, 2021·Seminars in Thrombosis and Hemostasis·Bingwen Eugene Fan, Christine Cheung

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Methods Mentioned

BETA
Coronary Aspiration
biopsy

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